Familial Mediterranean fever and scleroderma: a rare case report from Syria

Abstract Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease that affects the skin, joints, serous membranes and other various organs. Presentation of FMF can be solely but it can coexist with other conditions. It has been shown that it can be accompanied by various different...

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Bibliographic Details
Published in:Oxford Medical Case Reports 2023-10, Vol.2023 (10)
Main Authors: Nahas, Lujain, Al Khudari, Rawan, Khalil, Basheer
Format: Article
Language:English
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Case Report
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Summary:Abstract Familial Mediterranean fever (FMF) is an inherited autoinflammatory disease that affects the skin, joints, serous membranes and other various organs. Presentation of FMF can be solely but it can coexist with other conditions. It has been shown that it can be accompanied by various different disorders. Scleroderma is an autoimmune dermatologic condition that can present with systemic manifestations. No previous cases about the coexistence of FMF and scleroderma were previously documented, therefore we report the first case in Syria of a 10-year-old female that presented with clinically clear signs of both conditions (periodic fever and serous chest pain in addition to skin hyperpigmentation). The patient’s symptoms required full genetic testing along with the proper antibody detection and The diagnosis of FMF and scleroderma was confirmed by genetic testing and treatment was started.
ISSN:2053-8855
2053-8855
DOI:10.1093/omcr/omad111