Pulmonary lesions with asteroid bodies in a pig experimentally infected with Actinobacillus pleuropneumoniae serovar 15

Five pigs experimentally infected with Actinobacillus pleuropneumoniae serovar 15 isolated in our previous study were pathologically examined. One pig died at 2 days post inoculation (dpi) and four pigs were euthanized at 7 dpi. Autopsy revealed fibrinohemorrhagic pleuropneumonia in all pigs. Histop...

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Bibliographic Details
Published in:Journal of Veterinary Medical Science 2023, Vol.85(10), pp.1131-1135
Main Authors: TO, Ho, KONNAI, Masaki, TESHIMA, Kaho, TSUTSUMI, Nobuyuki, ITO, Soma, SATO, Masumi, SHIBUYA, Kazumoto, NAGAI, Shinya
Format: Article
Language:English
Subjects:
Abscesses
Actinobacillus pleuropneumoniae
asteroid body
Autopsy
Fibrin
Gram-negative bacilli
Hemorrhage
Inoculation
intratracheally
Leukocytes (neutrophilic)
Pathology
Pleuropneumonia
Pulmonary lesions
serovar 15
Splendore-Hoeppli material
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Summary:Five pigs experimentally infected with Actinobacillus pleuropneumoniae serovar 15 isolated in our previous study were pathologically examined. One pig died at 2 days post inoculation (dpi) and four pigs were euthanized at 7 dpi. Autopsy revealed fibrinohemorrhagic pleuropneumonia in all pigs. Histopathologically, the lesions were characterized by extensive hemorrhage and necrosis, fibrin deposition, and multifocal abscesses composed of numerous neutrophils including oat cells and numerous Gram-negative bacilli. In one survived pig, asteroid body formation was confirmed in the lung. The bacteria within the abscesses and asteroid bodies were immunohistochemically positive for antiserum raised against A. pleuropneumoniae serovar 15. This is the first report describing porcine pleuropneumonia with asteroid bodies in a pig experimentally infected with A. pleuropneumoniae serovar 15.
ISSN:0916-7250
1347-7439
DOI:10.1292/jvms.23-0202