Pulmonary lesions with asteroid bodies in a pig experimentally infected with Actinobacillus pleuropneumoniae serovar 15

Five pigs experimentally infected with Actinobacillus pleuropneumoniae serovar 15 isolated in our previous study were pathologically examined. One pig died at 2 days post inoculation (dpi) and four pigs were euthanized at 7 dpi. Autopsy revealed fibrinohemorrhagic pleuropneumonia in all pigs. Histop...

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Published in:Journal of Veterinary Medical Science 2023, Vol.85(10), pp.1131-1135
Main Authors: TO, Ho, KONNAI, Masaki, TESHIMA, Kaho, TSUTSUMI, Nobuyuki, ITO, Soma, SATO, Masumi, SHIBUYA, Kazumoto, NAGAI, Shinya
Format: Article
Language:English
Subjects:
Abscesses
Actinobacillus pleuropneumoniae
asteroid body
Autopsy
Fibrin
Gram-negative bacilli
Hemorrhage
Inoculation
intratracheally
Leukocytes (neutrophilic)
Pathology
Pleuropneumonia
Pulmonary lesions
serovar 15
Splendore-Hoeppli material
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cited_by cdi_FETCH-LOGICAL-c516t-9401a6f67395f9ee0a14d72a3a8d12d7bc0fb106f96b32ae29380ddba996b9e73
cites cdi_FETCH-LOGICAL-c516t-9401a6f67395f9ee0a14d72a3a8d12d7bc0fb106f96b32ae29380ddba996b9e73
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container_issue 10
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container_title Journal of Veterinary Medical Science
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creator TO, Ho
KONNAI, Masaki
TESHIMA, Kaho
TSUTSUMI, Nobuyuki
ITO, Soma
SATO, Masumi
SHIBUYA, Kazumoto
NAGAI, Shinya
description Five pigs experimentally infected with Actinobacillus pleuropneumoniae serovar 15 isolated in our previous study were pathologically examined. One pig died at 2 days post inoculation (dpi) and four pigs were euthanized at 7 dpi. Autopsy revealed fibrinohemorrhagic pleuropneumonia in all pigs. Histopathologically, the lesions were characterized by extensive hemorrhage and necrosis, fibrin deposition, and multifocal abscesses composed of numerous neutrophils including oat cells and numerous Gram-negative bacilli. In one survived pig, asteroid body formation was confirmed in the lung. The bacteria within the abscesses and asteroid bodies were immunohistochemically positive for antiserum raised against A. pleuropneumoniae serovar 15. This is the first report describing porcine pleuropneumonia with asteroid bodies in a pig experimentally infected with A. pleuropneumoniae serovar 15.
doi_str_mv 10.1292/jvms.23-0202
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subjects Abscesses
Actinobacillus pleuropneumoniae
asteroid body
Autopsy
Fibrin
Gram-negative bacilli
Hemorrhage
Inoculation
intratracheally
Leukocytes (neutrophilic)
Pathology
Pleuropneumonia
Pulmonary lesions
serovar 15
Splendore-Hoeppli material
title Pulmonary lesions with asteroid bodies in a pig experimentally infected with Actinobacillus pleuropneumoniae serovar 15
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