Cardiac Post-Chest Radiotherapy Complications in a 50-Year-Old Patient with Hodgkin Lymphoma

Lymphomas are a group of malignant tumors that originate in the lymphatic system. It is the most common type of blood cancer. It affects the lymph nodes, spleen, bone marrow, blood, and other organs. They can be aggressive or chronic. Hodgkin lymphoma survival rate is 2 in 100,000 people. Young adul...

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Bibliographic Details
Published in:Journal of clinical medicine 2023-10, Vol.12 (20), p.6506
Main Authors: Klotzka, Aneta, Sobańska, Karolina, Iwańczyk, Sylwia, Grygier, Marek, Woźniak, Patrycja, Błaszyk, Maciej, Rozwadowska, Natalia, Lesiak, Maciej
Format: Article
Language:English
Subjects:
Breast cancer
Cancer therapies
Cardiology
Cardiovascular disease
Care and treatment
Case Report
Case studies
Chronic illnesses
Clinical medicine
Complications and side effects
Coronary vessels
Dosimetry
Heart diseases
Heart failure
Hodgkin's disease
Ischemia
Lymphoma
Patients
Pericarditis
Radiation therapy
Radiotherapy
Risk factors
Vein & artery diseases
Womens health
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Summary:Lymphomas are a group of malignant tumors that originate in the lymphatic system. It is the most common type of blood cancer. It affects the lymph nodes, spleen, bone marrow, blood, and other organs. They can be aggressive or chronic. Hodgkin lymphoma survival rate is 2 in 100,000 people. Young adults aged 20–30 and people over 50 are most often affected. The prognosis of Hodgkin’s lymphoma is good, with a survival rate of up to 80 percent. Nevertheless, in 20–30 percent of patients who initially respond to treatment, the disease has a tendency to progress. The positive effect of radiotherapy (RT) on patients’ survival rates has been proven in many randomized clinical trials. Although the dose of chest RT has significantly reduced over the years, we still struggle with the long-term complications of post-RT repercussions, mainly because there is no established safe dose of RT affecting the heart. Other complications include earlier onset of coronary artery disease, early and late onset of pericarditis, valve degeneration (predominantly of the left heart), calcification of the aorta and its branches, heart failure, and arrhythmias. One patient can manifest each of the abovementioned complications, as in the present case. That is why choosing the right treatment strategy is crucial.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm12206506