Bridging Treatment Implementation Gaps in Patients with Heart Failure: JACC Focus Seminar

Heart failure (HF) is a leading cause of death and disability in older adults. Despite highest-quality evidence that supports the use of guideline-directed medical therapy (GDMT) to improve outcomes in HF, implementation of this evidence has been suboptimal. This review synthesizes implementation in...

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Bibliographic Details
Published in:Journal of the American College of Cardiology 2023-08, Vol.82 (6), p.544-558
Main Authors: Jalloh, Mohamed B., Averbuch, Tauben, Kulkarni, Prashanth, Granger, Christopher, Januzzi, James L., Zannad, Faiez, Yeh, Robert W, Yancy, Clyde, Fonarow, Gregg, Breathett, Khadijah, Gibson, C Michael, Van Spall, Harriette G.C.
Format: Article
Language:English
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Summary:Heart failure (HF) is a leading cause of death and disability in older adults. Despite highest-quality evidence that supports the use of guideline-directed medical therapy (GDMT) to improve outcomes in HF, implementation of this evidence has been suboptimal. This review synthesizes implementation interventions that increase the uptake of GDMT, discusses barriers and facilitators of implementation, summarizes conceptual frameworks in implementation science that could improve knowledge uptake, and offers suggestions for trial design that could better facilitate long-term implementation. By adopting principles of implementation science, policy makers, researchers, and clinicians can reduce the burden of HF on patients and healthcare systems.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2023.05.050