Health-Related Predictive Factors of Brazilian Children With Early Onset Scoliosis Using the EOSQ-24 and CHQ-PF50 Questionnaires

• Published in: International journal of spine surgery 2023-10, Vol.17 (5), p.638-644
• Main Authors: De Mendonça, Rodrigo Góes Medéa, Costa Martins, Wesley Wilian, Moraes Barros Fucs, Patricia Maria de, Gotfryd, Alberto Ofenhejm, Silber Caffaro, Maria Fernanda, Letaif, Olavo Biraghi, Marcon, Raphael, Cristante, Alexandre Fogaça, Kiyomoto, Henry Dan, Cardoso da Silva, Tânia Fernanda, Matsumoto, Hiroko, Vitale, Michael G., Meves, Robert
• Format: Article
• Language: English
• Subjects: Other and Special Categories
• ISSN: 2211-4599; 2211-4599
• DOI: 10.14444/8529

BACKGROUNDAssessing the quality of life (QOL) of children with early onset scoliosis (EOS) has been discussed recently. Therefore, the study aimed to apply and correlate the 24-item Early Onset Scoliosis Questionnaire (EOSQ-24) with the 50-item Childhood Health Questionnaire (CHQ-PF50) to find predictive factors impacting QOL.METHODSCross-sectional study involving a population of caregivers of patients with EOS. The sample consisted of 72 patients. Two research assistants applied the Portuguese version of the EOSQ-24 and CHQ-PF50 in 3 treatment centers. The EOSQ-24 assesses the subjective response of children with EOS from the parent's point of view. The CHQ is a self-administered questionnaire or parental proxy assessment of the psychological and social status of children aged 5 to 18 years.RESULTSOf 72 patients, 41 (56.9%) were females, mean age of 11.9 ± 4.2 years. The most common scoliosis was of neuromuscular origin (32%). The CHQ-PF50 showed that family-related items had significant scores. The most affected subcategory was physical function (45.5), and the least affected was mental health (90.8). Thus, the CHQ-PF50 PhS summary index was 27, and the CHQ-PF50 PsS was 71.7. Moreover, the critical categories for the EOSQ-24 questionnaire were daily life and physical function (45.1 and 47.8, respectively), and the least affected categories were transfer and pulmonary function (70.8 and 68.9, respectively). Four subcategories showed a strong correlation between both questionnaires: general health (r = 0.749, P < 0.001), physical function (r = 0.645, P < 0.001), bodily pain (r = 0.714, P < 0.001), and mental health (r = 0.424, P < 0.001). Using CHQ-PF50 as a dependent variable in multiple regression analysis (P = 0.028), the only variable affecting the scores was syndromic scoliosis (P = 0.019; 95% CI -27.4 to -2.5).CONCLUSIONA strong correlation between both questionnaires was seen for general health, physical function, bodily pain, and mental health. Syndromic scoliosis was a predictor of worse QOL according to the CHQ-PF50.LEVEL OF EVIDENCE: 2