Correlations between APACHE-II score and pressure parameters of mechanical ventilation in patients with ARDS and their value in prognostic evaluation

• Published in: Pakistan journal of medical sciences 2023-12, Vol.39 (6), p.1584-1588
• Main Authors: Lu, Wei, Zhang, Jiansong, Qiu, Yao, Fei, Na, Yin, Liansen
• Format: Article
• Language: English
• Subjects: Acute respiratory distress syndrome; Care and treatment; Chinese medicine; Correlation analysis; Disease; Health aspects; Hospitals; Medical prognosis; Mortality; Original; Physiology; United Kingdom; Ventilators
• ISSN: 1682-024X; 1681-715X
• DOI: 10.12669/pjms.39.6.7190

Objective: To investigate the correlations between APACHE-II score and pressure parameters of mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) and their value in prognostic evaluation. Methods: This was a retrospective study. The clinical data of 79 patients with ARDS treated in Shengzhou Hospital of Traditional Chinese Medicine from April 2020 to April 2022 were analyzed retrospectively. According to whether their APACHE-II scores were higher than 15, they were divided into low score group (n= 20) and high score group (n= 59). The plateau pressure (Pplat), driving pressure(ΔP) and mean airway pressure (Pmean) were compared. The correlation between APACHE-II score and pressure parameters of mechanical ventilation was analyzed. Based on the follow-up of 28-d survival, their Pplat, ΔP, Pmean and APACHE-II scores were compared. The value of APACHE-II score and pressure parameters in the prognostic evaluation of ARDS patients was analyzed. Results: Pplat, ΔP and Pmean in the low score group were significantly lower than those in the high score group(P