Benzodiazepines for Treatment-Resistant Major Depressive Disorder and Obsessive-Compulsive Disorder With Comorbid Mega Cisterna Magna

This article discusses the case of an adult woman with comorbid major depressive disorder (MDD) and obsessive-compulsive disorder (OCD). Due to her poor response to initial treatment regimens, a brain computed tomography (CT) was performed, revealing mega cisterna magna (MCM). Subsequently, she resp...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-10, Vol.15 (10)
Main Authors: Ismail, Arifah, Ab Razak, Asrenee, Sayuti, Khairil Amir, Phoa, Picholas Kian Ann
Format: Article
Language:English
Subjects:
Case reports
Case studies
Comorbidity
Cysts
Hydrocephalus
Mental disorders
Neurology
Neuroses
Obsessive compulsive disorder
Pathophysiology
Patients
Psychology
Psychosis
Radiology
Religion
Schizophrenia
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Summary:This article discusses the case of an adult woman with comorbid major depressive disorder (MDD) and obsessive-compulsive disorder (OCD). Due to her poor response to initial treatment regimens, a brain computed tomography (CT) was performed, revealing mega cisterna magna (MCM). Subsequently, she responded well to the addition of lorazepam, a benzodiazepine, along with fluvoxamine and quetiapine XR. The clinical significance of MCM and MDD-OCD remains partially understood. Thus, this case report aims to contribute to the literature and review the treatment of benzodiazepines in relation to MCM, MDD, and OCD comorbidities.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.46670