A Systematic Review of Phytochemistry, Nutritional Composition, and Pharmacologic Application of Species of the Genus Viola in Noncommunicable Diseases (NCDs)

Viola L. is the largest genus of the Violaceae family with more than 500 species across the globe. The present extensive literature survey revealed Viola species to be a group of important nutritional and medicinal plants used for the ethnomedicinal treatment of noncommunicable diseases (NCDs) such...

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Bibliographic Details
Published in:Evidence-based complementary and alternative medicine 2023, Vol.2023 (1), p.5406039
Main Authors: Batiha, Gaber El-Saber, Lukman, Halimat Yusuf, Shaheen, Hazem M., Wasef, Lamiaa, Hafiz, Amin A., Conte-Junior, Carlos Adam, Al-Farga, Ammar, Chamba, Moses V. M., Lawal, Bashir
Format: Article
Language:English
Subjects:
Acids
Analgesics
Antihypertensives
Asthma
Diabetes mellitus
Diuretics
Ethnopharmacology
Flavonoids
Immunomodulation
Inflammation
Leaves
Lung diseases
Medicinal plants
Morphology
Natural products
Neuroprotection
Oils & fats
Ovaries
Peptides
Pharmacokinetics
Phenylpropanoids
Review
Seeds
Stigma
Systematic review
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Summary:Viola L. is the largest genus of the Violaceae family with more than 500 species across the globe. The present extensive literature survey revealed Viola species to be a group of important nutritional and medicinal plants used for the ethnomedicinal treatment of noncommunicable diseases (NCDs) such as diabetes, asthma, lung diseases, and fatigue. Many plant species of this genus have also received scientific validation of their pharmacological activities including neuroprotective, immunomodulatory, anticancer, antihypertensive, antidyslipidemic, analgesic, antipyretic, diuretic, anti-inflammatory, anthelmintic, and antioxidant. Viola is highly rich in different natural products some of which have been isolated and identified in the past few decades; these include flavonoids terpenoids and phenylpropanoids of different pharmacological activities. The pharmacokinetics and clinical studies on this genus are lacking, and the present review is aimed at summarizing the current understanding of the ethnopharmacology, phytochemistry, nutritional composition, and pharmacological profile of medicinal plants from the Viola genus to reveal its therapeutic potentials, gaps, and subsequently open a new window for future pharmacological research.
ISSN:1741-427X
1741-4288
DOI:10.1155/2023/5406039