PSXIII-2 Effects of Probiotic Lactobacillus Rhamnosus on Growth Performance, Diarrhea Frequency, and Blood Biochemical Parameters of Weaned Pigs

• Published in: Journal of animal science 2023-11, Vol.101 (Supplement_3), p.571-572
• Main Authors: Kim, Kimoon, Kyoung, Hyunjin, Park, Kyeong Il, Kim, Yonghee, Ahn, Jinmu, Lee, Jae In, Ha, Sewon, Nam, Jinwook, Kang, Yonggu, Park, Youngmin, Shin, Ikcheol, Song, Minho
• Format: Article
• Language: English
• Subjects: Alanine; Alanine transaminase; Aspartate transaminase; Biochemistry; Blood; Body weight; Calcium; Calcium (blood); Chi-square test; Cholesterol; Creatinine; Diarrhea; Diet; Dietary supplements; Hogs; Lactobacilli; Magnesium; Mathematical models; Microorganisms; Parameters; Probiotics; Soybeans; Statistical models; Swine; Triglycerides; Urea; Visual observation; Weaning
• ISSN: 0021-8812; 1525-3163
• DOI: 10.1093/jas/skad281.669

Abstract Probiotics are microorganisms which have positive effects on human and animal gut health, and generally recognized as safe ingredients. This study was conducted to investigate the effects of probiotic Lactobacillus rhamnosus (LR) on growth performance, diarrhea frequency, and blood biochemical parameters of weaned pigs. A total of 100 weaned pigs [(Landrace × Yorkshire) × Duroc; 7.99 ± 0.85 kg of initial body weight (BW); 28 days old] were used in a 28-day trial. All pigs were randomly assigned to 2 dietary treatments in a randomized complete block design (block: initial BW) and there were 10 replication pens in each treatment with 5 pigs/pen. Dietary treatments were as follows: 1) a commercial weaner diet based on corn-soybean meal (CON), and 2) CON + 0.02% probiotic LR IDCC 3201 (PRO). All pigs were housed in an environmental controlled room and had free access to feed and water throughout the experimental period. Probiotic LR was obtained from commercial company (ILDONG Bioscience Co., Ltd., Pyeongtaek, Republic of Korea). Pigs BW was individually measured on day 1, 7, 14, and 28, and feed consumption was recorded on a pen basis on the same day to calculate average daily gain (ADG), average daily feed intake (ADFI), and gain to feed ratio (G:F). Diarrhea frequency was recorded by visual observation for 2 weeks after weaning and calculated as a percentage. Blood samples for biochemical parameters were collected from randomly selected one pig per pen on day 28 and analyzed by specific kit and clinical auto analyzer. Analysis items were total protein, aspartate transaminase, alanine transaminase, blood urea nitrogen, calcium (Ca), inorganic phosphorus, magnesium, total cholesterol, triglyceride, glucose, albumin, and creatinine. Data were analyzed using PROC GLM of SAS. Experimental unit was a pen. Statistical model for every measurement included dietary treatment as a main effect and initial BW as a covariate. The Chi-square test was used for diarrhea frequency. During day 1 to 7, 8 to 14, 1 to 14 and overall experiment date, ADG of pigs that fed PRO was greater (P < 0.05) than those fed CON. Pigs fed PRO had increased (P < 0.05) G:F during day 1 to 7 and 1 to 14 compared with those fed CON. Pigs fed PRO tended to have less (P < 0.10) diarrhea frequency during the first week of experiment than those fed CON. On blood biochemical parameters, pigs that fed PRO had greater (P < 0.05) concentrations of Ca (mg/dL) on day 28 than those fed CON. In conc