Dynamic change of PaO2 may affect the association between hyperoxemia and prognosis

[...]understanding the complexities of oxygen status assessment is pivotal in guiding clinical decision-making and ensuring optimal patient care. In clinical practice, oxygen partial pressure can be easily affected by parameters in mechanical ventilation [6], such as inspired oxygen fraction, minute...

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Bibliographic Details
Published in:Critical care (London, England) England), 2023-11, Vol.27 (1), p.1-434, Article 434
Main Author: Shen, Yanfei
Format: Article
Language:English
Subjects:
Cardiac arrest
Clinical outcomes
Critical care
Drug dosages
Hyperoxia
Intensive care
Matters Arising
Medical prognosis
Mortality
Oxygen therapy
Patients
Traumatic brain injury
Ventilators
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Summary:[...]understanding the complexities of oxygen status assessment is pivotal in guiding clinical decision-making and ensuring optimal patient care. In clinical practice, oxygen partial pressure can be easily affected by parameters in mechanical ventilation [6], such as inspired oxygen fraction, minute ventilation volume, etc. [...]relying solely on a static value of partial pressure of oxygen (PaO2) fails to capture the intricate dynamics of oxygenation in critically ill patients, and this limitation is particularly significant in the context of cardiac arrest patients, who often exhibit dynamic and rapidly changing physiological states. [...]this study contributed significantly to oxygen management in patients after cardiac arrest, and this work is very much appreciated!
ISSN:1364-8535
1364-8535
1366-609X
1466-609X
DOI:10.1186/s13054-023-04721-1