Chondroblastic Osteosarcoma of the Maxilla with Poor Response to Neoadjuvant Chemotherapy: A Rare Case Report and Updated Review of Literature

Craniofacial osteosarcoma is a relatively rare disease entity. In the craniofacial region, mandible is the commonest site followed by maxilla and skull bone. Due to its rare occurrence standard treatment guidelines are not formulated as in long bone or extremity sarcoma. Here we have reported a loca...

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Bibliographic Details
Published in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2023-12, Vol.75 (4), p.4041-4046
Main Authors: Nath, Jyotiman, Das, Anupam, Khanikar, Duncan, Ahmed, Shiraj, Kakati, Kaberi
Format: Article
Language:English
Subjects:
Bone cancer
Case reports
Clinical Report
Head and Neck Surgery
Jaw
Medicine
Medicine & Public Health
Oral cancer
Otorhinolaryngology
Sarcoma
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Summary:Craniofacial osteosarcoma is a relatively rare disease entity. In the craniofacial region, mandible is the commonest site followed by maxilla and skull bone. Due to its rare occurrence standard treatment guidelines are not formulated as in long bone or extremity sarcoma. Here we have reported a locally advanced case of a maxillary osteosarcoma of chondroblastic variant who was initially considered for neoadjuvant chemotherapy. However there was radiological evience of disease progression. Then the patient was considered for surgery followed by adjuvant radiotherapy. A literature review of the published cases of maxillary chondroblastic osteosarcoma has also been done here.
ISSN:2231-3796
0973-7707
DOI:10.1007/s12070-023-04037-0