Comparison of Intralesional Placentrex Versus Hyaluronidase and Dexamethasone Injection in the Symptomatic Management of Stage II Oral Submucous Fibrosis - a Prospective Study

Aim: The present study aimed to compare the effectiveness of intralesional placentrex versus hyaluronidase + dexamethasone injection in the symptomatic management of stage II OSMF. Materials and Methods: This was a non-randomized prospective study conducted over a period of 14 months at a tertiary r...

Full description

Saved in:
Bibliographic Details
Published in:Indian journal of otolaryngology, and head, and neck surgery and head, and neck surgery, 2023-12, Vol.75 (4), p.3530-3534
Main Authors: EK, Joshna, John, Bobby, Sharma, Ankit, Poorna T, Anish, Pangarikar, Anunay, Raj, Vishnu
Format: Article
Language:English
Subjects:
Head and Neck Surgery
Medicine
Medicine & Public Health
Original
Original Article
Otolaryngology
Otorhinolaryngology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim: The present study aimed to compare the effectiveness of intralesional placentrex versus hyaluronidase + dexamethasone injection in the symptomatic management of stage II OSMF. Materials and Methods: This was a non-randomized prospective study conducted over a period of 14 months at a tertiary referral center. Patients with clinical stage II OSMF were randomly grouped into A(n = 18) and B(n = 17). These patients were treated with weekly intralesional injection of placentrex and hyaluronidase + dexamethasone respectively, over a period of six weeks. Variables such as mouth opening, burning sensation and colour of mucosa were evaluated at baseline(T0), second week(T1), fourth week(T3), sixth week(T4) of follow up. A p-value 
ISSN:2231-3796
0973-7707
DOI:10.1007/s12070-023-04016-5