Anaplastic Large-Cell Lymphoma With Vitreous Humor Involvement

Purpose: To describe a case of T-cell lymphoma with bilateral vitreous involvement. Methods: A case report was reviewed, and a literature review, including search terms such as “anaplastic large-cell lymphoma (ALCL)” and “T-cell lymphoma with ocular involvement”, was performed. Results: A 56-year-ol...

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Bibliographic Details
Published in:Journal of vitreoretinal diseases (Print) 2023-11, Vol.7 (6), p.545-547
Main Authors: Caranfa, Jonathan T., Liang, Michelle C.
Format: Article
Language:English
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Case Reports
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Summary:Purpose: To describe a case of T-cell lymphoma with bilateral vitreous involvement. Methods: A case report was reviewed, and a literature review, including search terms such as “anaplastic large-cell lymphoma (ALCL)” and “T-cell lymphoma with ocular involvement”, was performed. Results: A 56-year-old man presented with slurred speech, left-sided weakness, and floaters in his right eye. He was found to have an enhancing right frontal lobe mass with biopsy positive for ALCL. The right eye demonstrated 2+ vitreous cell, with a vitreous biopsy consistent with ALCL. His floaters resolved, and the patient was asymptomatic until he developed floaters in his left eye 1½ years later. A subsequent vitreous biopsy revealed recurrence of ALCL in the fellow eye. Conclusions: ALCL is a rare T-cell lymphoma uncommonly reported as having vitreous infiltration.
ISSN:2474-1264
2474-1272
2474-1272
DOI:10.1177/24741264231191668