Emotional Stress and Immune Response in Surgery: A Psychoneuroimmunological Perspective

Psychoneuroimmunology (PNI) offers a deep dive into the nexus between emotional stress, immunity, and surgical outcomes. In this narrative review, we first trace PNI's historical roots, providing a foundational understanding of its evolution. We then dissect its significance across the surgical...

Full description

Saved in:
Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2023-11, Vol.15 (11), p.e48727-e48727
Main Authors: Reza, Taufiqa, Grezenko, Han, Barker, Chad, Bakht, Danyal, Faran, Nuzhat, Abdullah Yahya, Noor, Affaf, Maryam, Mohamed, Hana, Gasim, Rayan, I K H Almadhoun, Mohammed Khaleel, Rehman, Abdur, Kumar, Uday, Shehryar, Abdullah, Hasan, Abdul Haseeb
Format: Article
Language:English
Subjects:
Anesthesia
Anxiety
Behavior
Cognitive behavioral therapy
Communication
Cytokines
Emotions
Hormones
Immune system
Immunology
Influence
Internal Medicine
Mind body relationship
Mortality
Nervous system
Pain
Pathology
Physiology
Psychiatry
Psychological aspects
Psychology
Stress
Surgeons
Surgery
Surgical outcomes
Tumor necrosis factor-TNF
Well being
Wound healing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Psychoneuroimmunology (PNI) offers a deep dive into the nexus between emotional stress, immunity, and surgical outcomes. In this narrative review, we first trace PNI's historical roots, providing a foundational understanding of its evolution. We then dissect its significance across the surgical journey, from the preoperative phase through to postoperative recovery. It becomes evident through our exploration that emotional stress has profound implications for surgery, notably influencing wound healing rates, susceptibility to infections, and overall postoperative well-being. Among the arsenal to combat these challenges, interventions such as cognitive-behavioral therapy, mindfulness, and complementary practices such as meditation and yoga have emerged as potent tools. They not only mitigate stress but also play a pivotal role in enhancing immune function. However, the journey to optimizing surgical outcomes is not just about identifying effective interventions. A resounding theme is the importance of holistic care, ensuring that all patients have equitable access to these tools. As PNI continues to evolve, we stand at the precipice of a healthcare revolution, one that promises a blend of personalized care, anchored in a deep understanding of the mind-body connection in surgical contexts.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.48727