Application and Diagnostic Performance of Two-Dimensional Shear Wave Elastography and Liver Fibrosis Scores in Adults with Class 3 Obesity

There are no ideal non-invasive tests for assessing the severity of liver fibrosis in people with metabolic dysfunction-associated steatotic liver disease (MASLD) and class 3 obesity, where body habitus often makes imaging technically challenging. This study aimed to assess the applicability and dia...

Full description

Saved in:
Bibliographic Details
Published in:Nutrients 2023-12, Vol.16 (1), p.74
Main Authors: Chimoriya, Ritesh, Ho, Vincent, Wang, Ziqi Vincent, Chang, Ruby, Boumelhem, Badwi B, Simmons, David, Kormas, Nic, Gorrell, Mark D, Piya, Milan K
Format: Article
Language:English
Subjects:
Adolescent
Adult
Adults
Biomarkers
Biopsy
Body mass index
Chronic illnesses
Cross-Sectional Studies
Diabetes
Diagnosis
Elasticity Imaging Techniques
Electronic health records
Ethylenediaminetetraacetic acid
Female
Fibroblasts
Fibrosis
Gastrointestinal surgery
Humans
Liver
Liver cirrhosis
Liver Cirrhosis - diagnostic imaging
Liver Cirrhosis - etiology
Liver diseases
Male
Medical records
Metabolism
Obesity
Obesity - complications
Proteins
Risk Factors
Type 2 diabetes
Ultrasonic imaging
Weight control
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:There are no ideal non-invasive tests for assessing the severity of liver fibrosis in people with metabolic dysfunction-associated steatotic liver disease (MASLD) and class 3 obesity, where body habitus often makes imaging technically challenging. This study aimed to assess the applicability and diagnostic performance of two-dimensional shear wave elastography (2D-SWE), alongside several serum-based liver fibrosis scoring methods, in individuals with class 3 obesity. A cross-sectional study was conducted in patients aged ≥18 years and with a body mass index (BMI) ≥ 40 kg/m who were participants in a publicly funded multidisciplinary weight management program in South Western Sydney. The 2D-SWE was performed using the ElastQ Imaging (EQI) procedure with the Phillips EPIQ Elite series ultrasound. An EQI Median value of ≥6.43 kPa was taken as a cutoff score for significant fibrosis, and the scan was considered valid when the liver EQI IQR/Med value was
ISSN:2072-6643
2072-6643
DOI:10.3390/nu16010074