Functional Outcomes After Localized Prostate Cancer Treatment

Adverse outcomes associated with treatments for localized prostate cancer remain unclear. To compare rates of adverse functional outcomes between specific treatments for localized prostate cancer. An observational cohort study using data from 5 US Surveillance, Epidemiology, and End Results Program...

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Bibliographic Details
Published in:JAMA : the journal of the American Medical Association 2024-01, Vol.331 (4), p.302-317
Main Authors: Al Hussein Al Awamlh, Bashir, Wallis, Christopher J D, Penson, David F, Huang, Li-Ching, Zhao, Zhiguo, Conwill, Ralph, Talwar, Ruchika, Morgans, Alicia K, Goodman, Michael, Hamilton, Ann S, Wu, Xiao-Cheng, Paddock, Lisa E, Stroup, Antoinette, O'Neil, Brock B, Koyama, Tatsuki, Hoffman, Karen E, Barocas, Daniel A
Format: Article
Language:English
Subjects:
Aged
Androgen Antagonists - administration & dosage
Androgen Antagonists - adverse effects
Androgen Antagonists - therapeutic use
Androgens
Antigens
Brachytherapy
Cancer therapies
Deprivation
Epidemiology
Humans
Intestine
Irritation
Male
Middle Aged
Observational studies
Original Investigation
Patient Reported Outcome Measures
Patients
Prognosis
Prostate cancer
Prostate-specific antigen
Prostate-Specific Antigen - blood
Prostatectomy
Prostatectomy - adverse effects
Prostatectomy - methods
Prostatectomy - statistics & numerical data
Prostatic Neoplasms - blood
Prostatic Neoplasms - epidemiology
Prostatic Neoplasms - pathology
Prostatic Neoplasms - therapy
Radiation therapy
Radiotherapy - adverse effects
Radiotherapy - methods
Radiotherapy - statistics & numerical data
SEER Program - statistics & numerical data
Surveillance
United States - epidemiology
Urinary incontinence
Urinary Incontinence - epidemiology
Urinary Incontinence - etiology
Watchful Waiting - statistics & numerical data
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Description
Summary:Adverse outcomes associated with treatments for localized prostate cancer remain unclear. To compare rates of adverse functional outcomes between specific treatments for localized prostate cancer. An observational cohort study using data from 5 US Surveillance, Epidemiology, and End Results Program registries. Participants were treated for localized prostate cancer between 2011 and 2012. At baseline, 1877 had favorable-prognosis prostate cancer (defined as cT1-cT2bN0M0, prostate-specific antigen level
ISSN:0098-7484
1538-3598
1538-3598
DOI:10.1001/jama.2023.26491