Expert consensus on the role of supplementation in obstetrics and gynecology using modified delphi method

Purpose To reach a consensus among obstetrics and gynecology experts on the effects of micronutrient supplementation on fertility and pregnancy to aid clinicians in decision-making and create a unified approach to managing micronutrient deficiencies in women, by performing a modified Delphi study. M...

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Published in:Archives of gynecology and obstetrics 2024-02, Vol.309 (2), p.639-650
Main Authors: Soliman, Mohamed Yehia, Idris, Omima Abdel Fattah, Momtaz, Mohamed, Kortam, Mohamed Ashraf, ELNoury, Mohamed Amr, Saleh, Hisham Ali, Abulnour, Ayman, Ali, Ashraf Abo, Abbas, Mostafa, Shaaban, Omar M., din, Adel Shafik Salah El, Gaafar, Hassan, Orief, Yasser, Safwat, Michael
Format: Article
Language:English
Subjects:
Endocrinology
Fertility
General Gynecology
Gynecology
Human Genetics
Infertility
Medicine
Medicine & Public Health
Obstetrics
Obstetrics/Perinatology/Midwifery
Pregnancy
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Summary:Purpose To reach a consensus among obstetrics and gynecology experts on the effects of micronutrient supplementation on fertility and pregnancy to aid clinicians in decision-making and create a unified approach to managing micronutrient deficiencies in women, by performing a modified Delphi study. Methods A three-round modified Delphi process was conducted among a Delphi panel of 38 Egyptian experts to define recommendations regarding the role of supplementation on fertility and pregnancy in women of reproductive age. A literature review was performed and supporting evidence was graded to help guide the recommendations based on available evidence. Results A total of 62 statements were developed for discussion and voting. Out of the 62 statements, 60 statements reached expert consensus. Statements were divided into two domains. The first domain discussed the role of supplementation in fertility: optimizing natural fertility, polycystic ovary syndrome (PCOS), in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI), unexplained infertility, and endometriosis, whereas the second domain was concerned with the role of supplementation in pregnancy during the prenatal, antenatal, and postnatal periods. Conclusion In this work, a modified Delphi methodology was implemented to reach a consensus on the use of micronutrient supplementation in women of reproductive age. These recommendations can help clinicians in their practice, guide future research, and identify gaps in the market for the pharmaceutical industry. This clinical guidance can be extrapolated to similar communities.
ISSN:1432-0711
0932-0067
1432-0711
DOI:10.1007/s00404-023-07310-3