Renal transitional-cell carcinoma in two cats with chronic kidney disease

Two 12-year-old cats were diagnosed with chronic kidney disease (CKD) based on physical examination, clinicopathologic data and, in one case, abdominal ultrasound findings. Approximately 1 year after the initial diagnosis of CKD both cats developed renal transitional cell carcinoma (TCC) — bilateral...

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Bibliographic Details
Published in:Journal of feline medicine and surgery 2012-04, Vol.14 (4), p.280-284
Main Authors: Hanzlicek, Andrew S, Ganta, Chanran, Myers, Carl B, Grauer, Gregory F
Format: Article
Language:English
Subjects:
Animals
carcinoma
Carcinoma, Renal Cell - complications
Carcinoma, Renal Cell - pathology
Carcinoma, Renal Cell - veterinary
Carcinoma, Transitional Cell - complications
Carcinoma, Transitional Cell - pathology
Carcinoma, Transitional Cell - veterinary
Case Reports
Cat Diseases - diagnosis
Cat Diseases - pathology
Cats
clinical examination
Fatal Outcome
heart
Heart Neoplasms - secondary
Heart Neoplasms - veterinary
Intestinal Neoplasms - secondary
Intestinal Neoplasms - veterinary
Kidney Failure, Chronic - complications
Kidney Failure, Chronic - diagnosis
Kidney Failure, Chronic - veterinary
kidneys
large intestine
Lung Neoplasms - secondary
Lung Neoplasms - veterinary
lungs
Male
metastasis
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Summary:Two 12-year-old cats were diagnosed with chronic kidney disease (CKD) based on physical examination, clinicopathologic data and, in one case, abdominal ultrasound findings. Approximately 1 year after the initial diagnosis of CKD both cats developed renal transitional cell carcinoma (TCC) — bilateral in one cat. Based on post-mortem examination, one cat had no evidence of metastasis and the other had metastasis to the large intestine, heart and lungs. This is the first report of de novo bilateral renal TCC in a cat, as well as the first report of renal TCC developing in cats with previous history of confirmed CKD.
ISSN:1098-612X
1532-2750
1532-2750
DOI:10.1177/1098612X12437119