Predictors of pacemaker requirement in patients with implantable loop recorder and unexplained syncope: A systematic review and meta‐analysis

Identifying the underlying cause of unexplained syncope is crucial for appropriate management of recurrent syncopal episodes. Implantable loop recorders (ILRs) have emerged as valuable diagnostic tools for monitoring patients with unexplained syncope. However, the predictors of pacemaker requirement...

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Bibliographic Details
Published in:Clinical cardiology (Mahwah, N.J.) N.J.), 2024-02, Vol.47 (2), p.e24221-n/a
Main Authors: Zangiabadian, Moein, Soltani, Kiarash, Gholinejad, Yasaman, Yahya, Reyhane, Bastami, Shayan, Akbarzadeh, Mohammad Ali, Sharifian Ardestani, Mohammad, Aletaha, Azadeh
Format: Article
Language:English
Subjects:
Age
Cardiac arrhythmia
Electrocardiography
Fainting
Heart rate
ILR
implantable loop recorder
Medical prognosis
Meta-analysis
pacemaker
Pacemakers
Patients
predictor
Review
Reviews
Sinuses
Statistical analysis
Systematic review
unexplained syncope
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Summary:Identifying the underlying cause of unexplained syncope is crucial for appropriate management of recurrent syncopal episodes. Implantable loop recorders (ILRs) have emerged as valuable diagnostic tools for monitoring patients with unexplained syncope. However, the predictors of pacemaker requirement in patients with ILR and unexplained syncope remain unclear. In this study, we shed light on these prognostic factors. PubMed/MEDLINE, EMBASE, Web of Science, and Cochrane CENTRAL were systematically searched until May 04, 2023. Studies that evaluated the predictors of pacemaker requirement in patients with implantable loop recorder and unexplained syncope were included. The “Quality In Prognosis Studies” appraisal tool was used for quality assessment. The pooled odds ratio (OR) with 95% confidence intervals (CIs) was calculated. The publication bias was evaluated using Egger's and Begg's tests. Ten studies (n = 4200) were included. Right bundle branch block (OR: 3.264; 95% CI: 1.907–5.588, p 
ISSN:0160-9289
1932-8737
1932-8737
DOI:10.1002/clc.24221