Contrast-enhanced lesions on computerised tomography in multiple sclerosis

Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhanceme...

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Bibliographic Details
Published in:Journal of neurology, neurosurgery and psychiatry neurosurgery and psychiatry, 1978-08, Vol.41 (8), p.754-758
Main Authors: Harding, A E, Radue, E W, Whiteley, A M
Format: Article
Language:English
Subjects:
Adult
Cerebral Ventriculography
Diagnostic Errors
Female
Humans
Iothalamic Acid
Multiple Sclerosis - diagnostic imaging
Parietal Lobe - diagnostic imaging
Tomography, X-Ray Computed
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Summary:Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhancement in demyelinating disease is probably related to local breakdown of the blood-brain barrier.
ISSN:0022-3050
1468-330X
DOI:10.1136/jnnp.41.8.754