Lung abnormalities on computed tomography of Vietnamese patients with COVID-19 and the association with medical variables

• Published in: IJID regions 2024-03, Vol.10, p.183-190
• Main Authors: Trinh, Cong Dien, Le, Van Nam, Le, Van Nguyen Bang, Pham, Ngoc Thach, Le, Van Duyet
• Format: Article
• Language: English
• Subjects: COVID-19; CT scan; Lung CT abnormality; Lung injury; Lung involvement; Original Report
• ISSN: 2772-7076; 2772-7076
• DOI: 10.1016/j.ijregi.2024.01.006

•Lung injury was present in 57.6% of patients with COVID-19.•The most prevalent were ground-glass, consolidation, opacity, and nodular lung lesions.•Patients aged ≥60 years with co-morbidities and severity had a higher rate of lung injury.•Lung injury ≥25% was related with older age, the Delta variant, and severity.•A total of 100% of patients with lung injury died. Patients with COVID-19 may experience a lung injury without presenting clinical symptoms. Early detection of lung injury in patients with COVID-19 is required to enhance prediction and prevent severe progression. Lung lesions in patients with COVID-19 were defined using the Fleischner Society terminology. Chest computed tomography lesions and their correlation with demographic characteristics and medical variables were identified. Patients with mild and moderate COVID-19 had up to 45% lung injuries, whereas critical patients had 55%. However, patients with mild and moderate COVID-19 typically had low-level lung injuries. Ground-glass (68.1%), consolidation (48.8%), opacity (36.3%), and nodular (6.9%) lung lesions were the most prevalent in patients with COVID-19. Patients with COVID-19 infected with the Delta variant had worse lung injury than those infected with the Alpha and Omicron. People vaccinated with ≥2 doses showed a lower risk of lung injury than those vaccinated with