Atypical Papillary Dysplasia of the Bladder Neck

• Published in: Curēus (Palo Alto, CA) CA), 2024-01, Vol.16 (1), p.e52726
• Main Authors: Venishetty, Nikit, Trivedi, Meesha, Annabi, Jeffrey, Padilla, Angelica, Annabi, Hani
• Format: Article
• Language: English
• Subjects: Bladder cancer; Catheters; Cellular biology; Health sciences; Hematuria; Hemoglobin; Males; Pathology; Patients; Prostate; Urine; Urology
• ISSN: 2168-8184; 2168-8184
• DOI: 10.7759/cureus.52726

As the fourth most frequent disease in men, bladder cancer has a significant financial impact on healthcare. Because atypical dysplasia and papillary forms in bladder cancer are uncommon, there is a dearth of information on them. This study attempts to fill that gap. In the case study that is being presented, a 65-year-old man with a history of prostate cancer was admitted due to unusual urine cytology results that showed bladder papillary atypia. A distinct lesion on the bladder's dome that resembled a raspberry color was discovered by cystoscopy and transurethral resection of the bladder tumor (TURBT), which led to numerous biopsies and resections. Pathology demonstrated a significant urothelial proliferation. The study highlights the variety of morphologies found in atypical dysplastic lesions and the possibility that these lesions could develop into cancer. The significance of identifying atypical dysplastic lesions is emphasized in the study's conclusion, notably in patients with a history of prostate cancer, and highlights the need for further investigation in this domain.