Ethylene glycol poisoning requiring veno-arterial ECMO: A case report

Supportive care is the cornerstone of the poisoned patient’s treatment, waiting for eventual antidotes to act. We recently treated a case of a severe Ethylene Glycol intoxication with early-onset veno-arterial ECMO. The patient was taken to our Emergency Department with the suspicion of acute cerebr...

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Bibliographic Details
Published in:Perfusion 2024-03, Vol.39 (2), p.423-425
Main Authors: Orlando, Anita, Sciutti, Fabio, Colombo, Costanza NJ, Fiocco, Ermanno, Ambrosini, Emanuele, Coccolo, Matteo, Pellegrini, Carlo, Degani, Antonella, Biglia, Alessio, Mojoli, Francesco
Format: Article
Language:English
Subjects:
Acidosis
Age
Antidotes
Blood
Blood vessels
Case Reports
Computed tomography
Creatinine
Emergency medical care
Emergency medical services
Ethylene glycol
Ethylene Glycols
Extracorporeal Membrane Oxygenation - methods
Hemodynamics
Humans
Intoxication
Lactates
Male
Metabolic acidosis
Shock, Cardiogenic - chemically induced
Shock, Cardiogenic - therapy
Stroke
Veins
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Summary:Supportive care is the cornerstone of the poisoned patient’s treatment, waiting for eventual antidotes to act. We recently treated a case of a severe Ethylene Glycol intoxication with early-onset veno-arterial ECMO. The patient was taken to our Emergency Department with the suspicion of acute cerebrovascular accident, since he was found unconscious at home. The arterial blood gas and blood tests showed a severe metabolic acidosis with high serum lactates and creatinine levels. The cerebral Computed Tomography was negative. The rapid increase in serum lactates suggested Ethylene Glycol intoxication. Although the patient was not in shock yet, arterial and venous introducers were placed in to the femoral vessels so that when the patient showed the first signs of cardiogenic shock, veno-arterial ECMO could be initiated in a very short time. The hemodynamic state progressively improved and V-A ECMO was removed after 16 h of support with complete recovery.
ISSN:0267-6591
1477-111X
1477-111X
DOI:10.1177/02676591221141327