Exploring the Association Between Age Groups and Success Patterns in Platelet-Rich Plasma Therapy: A Cohort Study

Objective This study aimed to comprehensively examine the correlation between success trends in platelet-rich plasma (PRP) therapy and the advancing age of patients undergoing fertility interventions. Methods Female participants were categorized randomly into five age groups undergoing PRP or conven...

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Published in:Curēus (Palo Alto, CA) CA), 2024-02, Vol.16 (2), p.e53418-e53418
Main Authors: Dutta, Shilpa, More, Akash, Shrivastava, Deepti, Choudhary, Namrata, Wanjari, Mayur, Anjankar, Vaibhav P, Anjankar, Ashish, Chopra, Mehak, Khemani, Shivani
Format: Article
Language:English
Subjects:
Age groups
Anatomy
Blood platelets
Cohort analysis
Endometrium
Growth factors
Hormone replacement therapy
In vitro fertilization
Infertility
Menstruation
Obstetrics/Gynecology
Ovaries
Patients
Plasma
Pregnancy
Success
Therapeutics
Variance analysis
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Summary:Objective This study aimed to comprehensively examine the correlation between success trends in platelet-rich plasma (PRP) therapy and the advancing age of patients undergoing fertility interventions. Methods Female participants were categorized randomly into five age groups undergoing PRP or conventional hormone replacement therapy. Procedures included controlled ovarian stimulation, escalating estrogen dosage, gonadotrophin injections, and embryo transfer post-ovulation trigger. A pivotal PRP intervention was provided to half of the age sub-groups, and endometrial thickness was assessed 24 hours prior to embryo transfer. Statistical analysis employed SPSS 26.0 for Windows Student Version (IBM Inc., Armonk, New York), incorporating descriptive statistics, one-way analysis of variance (ANOVA), Tukey's honestly significant difference (HSD) test to explore age-PRP success relationships (p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.53418