Effects of chemotherapy treatment on muscle strength indicators, functional capacity and biopsychosocial aspects of women with breast cancer

• Published in: American journal of cancer research 2024-01, Vol.14 (2), p.762-773
• Main Authors: Alves, Rafael Ribeiro, Marques, Vitor Alves, da Silva, Weder Alves, Freitas-Junior, Ruffo, da Cruz, Anderson Miguel, Del Vecchio, Fabrício Boscolo, Rosa, Victor Domingos Lisita, Vieira, Carlos Alexandre
• Format: Article
• Language: English
• Subjects: Original
• ISSN: 2156-6976; 2156-6976
• DOI: 10.62347/NLDK3210

Evidences on the effects of chemotherapy treatment cycles on measures of muscle, mental state, social and cognitive performance are scarce. The objective of this study was to analyze the effects of chemotherapy cycles on muscle strength and activation, functional capacity, quality of life, fatigue and anxiety of women with breast cancer. Therefore, twenty-two women divided into a treatment group (n = 10; 46.6 ± 9.6 years) and control group (n = 12; 51.6 ± 7.0 years) participated in the study. Analysis of muscle performance, quality of life, fatigue and anxiety after the 2 and 4 cycle of chemotherapy with anthracyclines were performed in women with breast cancer (TRA) and compared to healthy women (CTR). Two-way ANOVA was used to compare the variance of the means and the significance level was set as P≤0.05. The results showed Differences in the muscular activation of the between the groups at post time (P = 0.038), as well as in the sit and stand test in the baseline (P