Mechanical Hatching as a Therapeutic Intervention for Improving Implantation Rate in a 32-Year-Old Female With Recurrent Implantation Failures: A Case Report

This case report explores the application of mechanical hatching as a successful intervention in the treatment of primary infertility for a couple with a consanguineous marriage history and recurrent implantation failure. A 32-year-old female patient and her 37-year-old spouse, after six years of un...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-02, Vol.16 (2), p.e53709
Main Authors: Kakatikar, Rabia, Bawaskar, Pranita A, Gajbe, Ujwal, More, Akash, Nair, Nancy
Format: Article
Language:English
Subjects:
Anatomy
Case reports
Couples
Embryos
Endometrium
Failure
Females
Fertility
Follicles
In vitro fertilization
Infertility
Marriage
Motility
Obstetrics/Gynecology
Other
Ovaries
Personal relationships
Pregnancy
Reproductive technologies
Sperm
Success
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Summary:This case report explores the application of mechanical hatching as a successful intervention in the treatment of primary infertility for a couple with a consanguineous marriage history and recurrent implantation failure. A 32-year-old female patient and her 37-year-old spouse, after six years of unsuccessful attempts to conceive, underwent multiple intrauterine insemination (IUI) and in vitro fertilization (IVF) and embryo transfer (ET) cycles without success. Normal parameters were observed in semen analysis and hormone tests for the male and female partners, respectively. Despite a series of failed assisted reproductive technology (ART) procedures, the implementation of mechanical hatching using partial zona dissection (PZD) pipettes led to a positive pregnancy outcome. The case underscores the potential efficacy of individualized approaches, specifically mechanical hatching, in addressing challenges associated with implantation failure, offering hope to couples facing infertility issues.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.53709