Vitamin D-A New Therapeutic Target in the Management of Type 2 Diabetes Patients

: Vitamin D is a fat-soluble vitamin that prevents cardiovascular diseases and diabetes mellitus (DM). The present research aimed to study the impact of 25-hydroxyvitamin D (25(OH)D) level on the health status of patients with type 2 DM (T2DM) hospitalized in the "Pius Brînzeu" Emergency C...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-02, Vol.13 (5), p.1390
Main Authors: Albai, Oana, Braha, Adina, Timar, Bogdan, Golu, Ioana, Timar, Romulus
Format: Article
Language:English
Subjects:
Alfacalcidol
Body mass index
Calcifediol
Cardiovascular diseases
Complications and side effects
Dementia
Diabetes
Diet therapy
Health aspects
Hemoglobin
Liver
Prevention
Risk factors
Skin
Smooth muscle
Software
Statistical analysis
Type 2 diabetes
Variables
Vitamin D
Vitamin deficiency
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Summary:: Vitamin D is a fat-soluble vitamin that prevents cardiovascular diseases and diabetes mellitus (DM). The present research aimed to study the impact of 25-hydroxyvitamin D (25(OH)D) level on the health status of patients with type 2 DM (T2DM) hospitalized in the "Pius Brînzeu" Emergency Clinical County University Hospital in Timisoara, Romania. : The study retrospectively included 160 patients with T2DM who were clinically and biologically evaluated during hospitalization. : 13.1% of patients had optimal, 23.1% insufficient, and 63.8% deficient 25(OH)D values. Patients with 25(OH)D deficiency presented poorer glycemic control and were older, with higher weight, but had altered renal function, anemia, and lower iron values. Also, patients with associated neoplasia, diabetic neuropathy, cardiovascular disease (CVD), dementia, and grade 3 arterial hypertension (HTN) had lower values of 25(OH)D. An age > 55 years (sensitivity 69.9, specificity 82.5, AUROC 0.786, 0.001) and an HbA1c > 7.7% (sensitivity 89.3, specificity 92.9, AUROC 0.938, 0.001) predict 25(OH)D deficiency in T2DM patients. : Vitamin D influences almost every system and organ in the body, so it should be a routine test for all patients with DM to correct the deficiency and prevent other diseases and complications.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13051390