Electrospinning Silk-Fibroin-Based Fibrous Membranes with AgNPs for Antimicrobial Application

Silk fibroin (SF) has excellent biocompatibility and is one of the most commonly used polymer materials. However, SF fibers have serious drawbacks as antibacterial materials due to their lack of stability and bacterial resistance. Therefore, it is of paramount significance to enhance the stability a...

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Bibliographic Details
Published in:Polymers 2024-02, Vol.16 (5), p.648
Main Authors: Li, Qing, Gong, Hongyu, Jia, Xiang, Wang, Ran, Liu, Zhiwei, Zhang, Lexin, Li, Jisheng, Jiao, Tifeng
Format: Article
Language:English
Subjects:
Antibacterial materials
Biocompatibility
Cancer
Cellulose acetate
E coli
Fibers
Hemodialysis
Identification and classification
Materials selection
Mechanical properties
Medical materials
Membranes
Nanoparticles
Polyethylene
Polymers
Properties
Silk
Silk fibroin
Silver
Stability
Textiles
Wound healing
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Summary:Silk fibroin (SF) has excellent biocompatibility and is one of the most commonly used polymer materials. However, SF fibers have serious drawbacks as antibacterial materials due to their lack of stability and bacterial resistance. Therefore, it is of paramount significance to enhance the stability and bolster the bacterial resistance of SF fibers. In this study, SF fibers were fabricated and loaded with Ag nanoparticles (AgNPs) to improve the antimicrobial properties of the fibers. The impact of reduction conditions on the size of AgNPs was also investigated. In an antibacterial test, the fibers that were prepared exhibited over 98% bacterial resistance against ( ) and ( ). Therefore, as an efficient antibacterial material, these fibers are expected to become a candidate material in medical and textile fields. This study offers a novel approach for the utilization of SF fibers in the realm of antibacterial applications.
ISSN:2073-4360
2073-4360
DOI:10.3390/polym16050648