A Determination of Salivary and Serum Glucose Levels in Patients With Type II Diabetes Mellitus

The aim of this work was to determine and compare serum and salivary glucose levels in patients with type II diabetes mellitus (DM). This study had an overall sample size of 100, which consisted of male and female volunteers aged 30-67 years. Both in-depth interviews and physical tests were conducte...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-02, Vol.16 (2), p.e54395-e54395
Main Authors: Anjum, Bushra, Soorneedi, Neeharika, Swathi, J, Imran, Mohammed, Gaddikeri, Kavitha, Nallapu, Anoop
Format: Article
Language:English
Subjects:
Carbohydrates
Dentistry
Diabetes
Exocrine glands
Fluorides
Glucose
Hyperglycemia
Insulin resistance
Metabolism
Pathology
Patients
Proteins
Sample size
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Summary:The aim of this work was to determine and compare serum and salivary glucose levels in patients with type II diabetes mellitus (DM). This study had an overall sample size of 100, which consisted of male and female volunteers aged 30-67 years. Both in-depth interviews and physical tests were conducted. Blood and saliva were collected from the participants while fasting, which were analyzed to determine the levels of salivary alpha-amylase (α-amylase). Both the subjects and the controls were instructed to test their blood glucose levels while fasting and it was suggested that HbA1c values will be used for diagnosing diabetes following the guidelines of the American Diabetes Association, Centers for Disease Control, and World Health Organization. The average age of the control group (Category A) was noted as 47.52±6.28 years, and that of the study group (Category B) was 49.17±7.25 years. In Category A, female (n=23) were 46%, and 54% were male (n=27); and 40% of the people in Category B were female (n=20), and 60% were male (n=30). The majority of patients (54%) in Category B displayed an average level of DM control (n=27), followed by poor control (24%. n=12), well-controlled (20%, n=10), and uncontrolled DM (2%, n=1). Category A had an average salivary α-amylase concentration of 3.1±0.88 U/L, whereas that of Category B was 12.06±2.36 U/L. Thus, the mean salivary α-amylase level of Category B was found to be much higher than that of Category A, and this difference was statistically significant (p
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.54395