Exploring the photocatalytic and photodynamic effects of BODIPY-linked titanium dioxide nanoparticles

• Published in: Turkish journal of chemistry 2023-01, Vol.47 (6), p.1407-1419
• Main Author: Demirel Topel, Seda
• Format: Article
• Language: English
• ISSN: 1300-0527; 1300-0527; 1303-6130
• DOI: 10.55730/1300-0527.3623

This study aimed to investigate the photocatalytic and photodynamic actions of a 2,6-diiodinated-BODIPY (2,6-diI -Bod) photosensitizer (PS) covalently linked to TiO nanoparticles (NPs). The TiO NPs were synthesized utilizing the hydrothermal technique, yielding an average particle size of 4-5 nm as ascertained by transmission electron microscopy and 6.4 nm as determined by dynamic light scattering measurements. The integration of the nonsoluble Bod PS to TiO NPs provided increased dispersibility in physiological media, making it more applicable to photodynamic therapy applications. Bod-TiO NPs exhibited moderate efficiency of 56.9% in singlet oxygen generation. Additionally, the photocatalytic behavior of the TiO NPs was evaluated using methylene blue and 83.8% photodegradation efficiency was observed. The loading efficiency and loading content of the Bod PS were found to be 90.8% and 54.5%, respectively. These results suggest that Bod-TiO NPs possess higher dispersibility in aqueous solutions, moderate photocatalytic activity, and potential for photodynamic therapy applications.