Intense prostate-specific membrane antigen receptor expression in coronary artery pypass graft scar tissue: A potential molecular imaging pitfall

68Gallium-PSMA positron emission tomography/computer tomography has been utilized recently for the diagnosis and staging of prostate cancer. PSMA is a transmembrane protein that is expressed not only in the prostate gland but also in other tissues. While some pitfalls have been addressed, there are...

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Bibliographic Details
Published in:Acta radiologica open 2024-02, Vol.13 (2), p.20584601241240318
Main Authors: Al-Ibraheem, Akram, Abdlkadir, Ahmed Saad, Al-Hajaj, Nabeela, Khalaf, Aysar, Salah, Samer
Format: Article
Language:English
Subjects:
Case Report
Computed tomography
Coronary artery
Medical imaging
Positron emission
Positron emission tomography
Prostate
Prostate cancer
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Summary:68Gallium-PSMA positron emission tomography/computer tomography has been utilized recently for the diagnosis and staging of prostate cancer. PSMA is a transmembrane protein that is expressed not only in the prostate gland but also in other tissues. While some pitfalls have been addressed, there are still uncertainties. Herein, we report a 79-year-old male with prostate cancer who underwent a PSMA scan after coronary artery bypass graft surgery, revealing disease progression and PSMA-avid foci at the surgical stitch sites. This report discusses the immunohistochemical and molecular imaging mechanisms underlying PSMA expression in surgical scar tissues, providing critical insights for optimizing radiologic reporting in such situations.
ISSN:2058-4601
2058-4601
DOI:10.1177/20584601241240318