Diagnosis of poorly differentiated adenocarcinoma of the stomach by confocal laser endomicroscopy: A case report

• Published in: World journal of clinical cases 2024-03, Vol.12 (8), p.1481-1486
• Main Authors: Lou, Jia-Xin, Wu, Yong, Huhe, Muren, Zhang, Jing-Jie, Jia, Dong-Wu, Jiang, Zhen-Yu
• Format: Article
• Language: English
• Subjects: Case Report
• ISSN: 2307-8960; 2307-8960
• DOI: 10.12998/wjcc.v12.i8.1481

In recent years, confocal laser endomicroscopy (CLE) has become a new endoscopic imaging technology at the microscopic level, which is extensively performed for real-time histological examination. CLE can be performed to distinguish benign from malignant lesions. In this study, we diagnosed using CLE an asymptomatic patient with poorly differentiated gastric adenocarcinoma. A 63-year-old woman was diagnosed with gastric mucosal lesions, which may be gastric cancer, in the small curvature of the stomach by gastroscopy. She consented to undergo CLE for morphological observation of the gastric mucosa. Through the combination of CLE diagnosis and postoperative pathology, the intraoperative CLE diagnosis was considered to be reliable. According to our experience, CLE can be performed as the first choice for the diagnosis of gastric cancer. CLE has several advantages over pathological diagnosis. We believe that CLE has great potential in the diagnosis of benign and malignant gastric lesions.