Transnasal cooling: New prospect of selective hypothermia in acute ischemic stroke

Rapid and selective therapeutic hypothermia is a promising neuroprotective method for acute ischemic stroke. A recent study developed a simple but efficient technique of transnasal cooling, in which air at ambient temperature was passed through standard nasal cannula to induce evaporative cooling of...

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Bibliographic Details
Published in:Journal of cerebral blood flow and metabolism 2024-02, Vol.44 (2), p.310-312
Main Authors: Chen, Xi, Xu, Shuaili, Li, Ming, Wu, Di, Ji, Xunming
Format: Article
Language:English
Subjects:
Animals
Brain - blood supply
Brain Ischemia
Commentaries
Hypothermia - drug therapy
Hypothermia, Induced - methods
Ischemic Stroke - therapy
Stroke - drug therapy
Swine
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Summary:Rapid and selective therapeutic hypothermia is a promising neuroprotective method for acute ischemic stroke. A recent study developed a simple but efficient technique of transnasal cooling, in which air at ambient temperature was passed through standard nasal cannula to induce evaporative cooling of the brain. Selective brain temperature decrease was achieved within 25 minutes in piglets. It is a major step forward to initiate early brain cooling. However, it is still necessary to devise a more comprehensive strategy to enhance the benefits of selective brain cooling in the era of effective reperfusion.
ISSN:0271-678X
1559-7016
1559-7016
DOI:10.1177/0271678X231211726