Liver regeneration of living donor after liver donation for transplantation: Disparity in the left and right remnant liver

Donor safety is crucial for living donor liver transplantation (LDLT), and sufficient liver regeneration significantly affects outcomes of living donors. This study aimed to investigate clinical factors associated with liver regeneration in living donors. The study retrospectively reviewed 380 livin...

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Published in:Medicine (Baltimore) 2024-04, Vol.103 (14), p.e37632-e37632
Main Authors: Wang, Wei-Cheng, Wu, Tsung-Han, Hung, Hao-Chien, Lee, Jin-Chiao, Cheng, Chih-Hsien, Wang, Yu-Chao, Lee, Chen-Fang, Wu, Ting-Jung, Chou, Hong-Shiue, Chan, Kun-Ming, Lee, Wei-Chen
Format: Article
Language:English
Subjects:
Observational Study
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Summary:Donor safety is crucial for living donor liver transplantation (LDLT), and sufficient liver regeneration significantly affects outcomes of living donors. This study aimed to investigate clinical factors associated with liver regeneration in living donors. The study retrospectively reviewed 380 living donors who underwent liver donation at Chang Gung Memorial Hospital in Linkou. The clinical characteristics and medical parameters of donors were analyzed and compared according to liver donation graft type. There were 355 donors (93.4%) with right hemi-liver donations and 25 donors (6.6%) with left hemi-liver donations. Left hemi-liver donors had a higher body mass index (BMI) and a larger ratio of remnant liver volume (RLV) to total liver volume (TLV). However, the 2 groups showed no significant difference in the liver regeneration ratio. The type of remnant liver (P 
ISSN:0025-7974
1536-5964
DOI:10.1097/MD.0000000000037632