Loading…
Analysis of retromuscular drain output and postoperative outcomes for heavyweight versus mediumweight polypropylene mesh following open ventral hernia repair
Purpose Heavyweight polypropylene (HWPP) mesh is thought to increase inflammatory response and delay tissue integration compared to mediumweight (MWPP). Reactive fluid volume (i.e., drain output) may be a reasonable surrogate for integration. We hypothesized that daily drain output is higher with HW...
Saved in:
| Published in: | Hernia : the journal of hernias and abdominal wall surgery 2024-04, Vol.28 (2), p.637-642 |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | cdi_FETCH-LOGICAL-c426t-7ba89c838a266da1f6276c2a1c19fbe29a67e4cc3b593fe322586c5811349a5a3 |
| container_end_page | 642 |
| container_issue | 2 |
| container_start_page | 637 |
| container_title | Hernia : the journal of hernias and abdominal wall surgery |
| container_volume | 28 |
| creator | Essani, V. Maskal, S. M. Ellis, R. C. Messer, N. Tu, C. Miller, B. T. Petro, C. C. Beffa, L. R. A. Krpata, D. M. Prabhu, A. S. Rosen, M. J. |
| description | Purpose
Heavyweight polypropylene (HWPP) mesh is thought to increase inflammatory response and delay tissue integration compared to mediumweight (MWPP). Reactive fluid volume (i.e., drain output) may be a reasonable surrogate for integration. We hypothesized that daily drain output is higher with HWPP compared to MWPP in open retromuscular ventral hernia repair (VHR).
Methods
This is a post-hoc analysis of a multicenter, randomized clinical trial conducted March 2017–April 2019 comparing MWPP and HWPP for VHR. Retromuscular drain output in milliliters was measured at 24-h intervals up to postoperative day seven. Univariate analyses compared differences in daily drain output and time to drain removal. Multivariable analyses compared total drain output and wound morbidity within 30 days and hernia recurrence at 1 year.
Results
288 patients were included; 140 (48.6%) HWPP and 148 (51.4%) MWPP. Daily drain output for days 1–3 was higher for HWPP vs. MWPP (total volume: 837.8 mL vs. 656.5 mL) (
p
0.05). Median drain removal time was 5 days for both groups. Total drain output was not predictive of 30-day wound morbidity (
p
> 0.05) or hernia recurrence at 1 year (OR 1,
p
= 0.29).
Conclusion
While HWPP mesh initially had higher drain outputs, it rapidly returned to levels similar to MWPP by postoperative day three and there was no difference in clinical outcomes. We believe that drains placed around HWPP mesh can be managed similarly to MWPP mesh. |
| doi_str_mv | 10.1007/s10029-024-02972-7 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10997680</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2932432914</sourcerecordid><originalsourceid>FETCH-LOGICAL-c426t-7ba89c838a266da1f6276c2a1c19fbe29a67e4cc3b593fe322586c5811349a5a3</originalsourceid><addsrcrecordid>eNp9UcuOFCEUrRiN89AfcGFI3Lgp5VUFrMxkoo7JJG50TW7TVDcTCkooelIfM_8qY7Xj6MIFcMN5cMhpmlcEvyMYi_e57lS1mPK6lKCteNKcEsplqyjmTx_NJ81ZzjcYY8l7-bw5YZJj1Qly2txdBPBLdhnFASU7pziWbIqHhLYJXECxzFOZEYQtmmKe42QTzO5g7wETR5vREBPaWzgst9bt9jM62JRLRqPdujIe76bolynFafE22ArlfZV5H29d2KHqGaoqzAl8dUrBQY0ygUsvmmcD-GxfHs_z5vunj98ur9rrr5-_XF5ct4bTfm7FBqQykkmgfb8FMvRU9IYCMUQNG0sV9MJyY9imU2ywjNJO9qaThDCuoAN23nxYfaeyqbnNmkVPyY2QFh3B6b-R4PZ6Fw-aYKVEL3F1eHt0SPFHsXnWo8vGeg_BxpI1VYxyRhXhlfrmH-pNLKnWkDXDjIlOMqwqi64sk2LOyQ4PaQjW9_XrtX5d69e_6teiil4__seD5HfflcBWQq5Q2Nn05-3_2P4EooTBMQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>3033758309</pqid></control><display><type>article</type><title>Analysis of retromuscular drain output and postoperative outcomes for heavyweight versus mediumweight polypropylene mesh following open ventral hernia repair</title><source>Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List</source><creator>Essani, V. ; Maskal, S. M. ; Ellis, R. C. ; Messer, N. ; Tu, C. ; Miller, B. T. ; Petro, C. C. ; Beffa, L. R. A. ; Krpata, D. M. ; Prabhu, A. S. ; Rosen, M. J.</creator><creatorcontrib>Essani, V. ; Maskal, S. M. ; Ellis, R. C. ; Messer, N. ; Tu, C. ; Miller, B. T. ; Petro, C. C. ; Beffa, L. R. A. ; Krpata, D. M. ; Prabhu, A. S. ; Rosen, M. J.</creatorcontrib><description>Purpose
Heavyweight polypropylene (HWPP) mesh is thought to increase inflammatory response and delay tissue integration compared to mediumweight (MWPP). Reactive fluid volume (i.e., drain output) may be a reasonable surrogate for integration. We hypothesized that daily drain output is higher with HWPP compared to MWPP in open retromuscular ventral hernia repair (VHR).
Methods
This is a post-hoc analysis of a multicenter, randomized clinical trial conducted March 2017–April 2019 comparing MWPP and HWPP for VHR. Retromuscular drain output in milliliters was measured at 24-h intervals up to postoperative day seven. Univariate analyses compared differences in daily drain output and time to drain removal. Multivariable analyses compared total drain output and wound morbidity within 30 days and hernia recurrence at 1 year.
Results
288 patients were included; 140 (48.6%) HWPP and 148 (51.4%) MWPP. Daily drain output for days 1–3 was higher for HWPP vs. MWPP (total volume: 837.8 mL vs. 656.5 mL) (
p
< 0.001), but similar on days 4–7 (
p
> 0.05). Median drain removal time was 5 days for both groups. Total drain output was not predictive of 30-day wound morbidity (
p
> 0.05) or hernia recurrence at 1 year (OR 1,
p
= 0.29).
Conclusion
While HWPP mesh initially had higher drain outputs, it rapidly returned to levels similar to MWPP by postoperative day three and there was no difference in clinical outcomes. We believe that drains placed around HWPP mesh can be managed similarly to MWPP mesh.</description><identifier>ISSN: 1248-9204</identifier><identifier>ISSN: 1265-4906</identifier><identifier>EISSN: 1248-9204</identifier><identifier>DOI: 10.1007/s10029-024-02972-7</identifier><identifier>PMID: 38409571</identifier><language>eng</language><publisher>Paris: Springer Paris</publisher><subject>Abdominal Surgery ; Hernia ; Hernias ; Inflammation ; Medicine ; Medicine & Public Health ; Morbidity ; Original ; Original Article ; Polypropylene ; Wounds</subject><ispartof>Hernia : the journal of hernias and abdominal wall surgery, 2024-04, Vol.28 (2), p.637-642</ispartof><rights>The Author(s) 2024</rights><rights>2024. The Author(s).</rights><rights>The Author(s) 2024. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c426t-7ba89c838a266da1f6276c2a1c19fbe29a67e4cc3b593fe322586c5811349a5a3</cites><orcidid>0000-0001-7072-1944</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,780,784,885,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38409571$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Essani, V.</creatorcontrib><creatorcontrib>Maskal, S. M.</creatorcontrib><creatorcontrib>Ellis, R. C.</creatorcontrib><creatorcontrib>Messer, N.</creatorcontrib><creatorcontrib>Tu, C.</creatorcontrib><creatorcontrib>Miller, B. T.</creatorcontrib><creatorcontrib>Petro, C. C.</creatorcontrib><creatorcontrib>Beffa, L. R. A.</creatorcontrib><creatorcontrib>Krpata, D. M.</creatorcontrib><creatorcontrib>Prabhu, A. S.</creatorcontrib><creatorcontrib>Rosen, M. J.</creatorcontrib><title>Analysis of retromuscular drain output and postoperative outcomes for heavyweight versus mediumweight polypropylene mesh following open ventral hernia repair</title><title>Hernia : the journal of hernias and abdominal wall surgery</title><addtitle>Hernia</addtitle><addtitle>Hernia</addtitle><description>Purpose
Heavyweight polypropylene (HWPP) mesh is thought to increase inflammatory response and delay tissue integration compared to mediumweight (MWPP). Reactive fluid volume (i.e., drain output) may be a reasonable surrogate for integration. We hypothesized that daily drain output is higher with HWPP compared to MWPP in open retromuscular ventral hernia repair (VHR).
Methods
This is a post-hoc analysis of a multicenter, randomized clinical trial conducted March 2017–April 2019 comparing MWPP and HWPP for VHR. Retromuscular drain output in milliliters was measured at 24-h intervals up to postoperative day seven. Univariate analyses compared differences in daily drain output and time to drain removal. Multivariable analyses compared total drain output and wound morbidity within 30 days and hernia recurrence at 1 year.
Results
288 patients were included; 140 (48.6%) HWPP and 148 (51.4%) MWPP. Daily drain output for days 1–3 was higher for HWPP vs. MWPP (total volume: 837.8 mL vs. 656.5 mL) (
p
< 0.001), but similar on days 4–7 (
p
> 0.05). Median drain removal time was 5 days for both groups. Total drain output was not predictive of 30-day wound morbidity (
p
> 0.05) or hernia recurrence at 1 year (OR 1,
p
= 0.29).
Conclusion
While HWPP mesh initially had higher drain outputs, it rapidly returned to levels similar to MWPP by postoperative day three and there was no difference in clinical outcomes. We believe that drains placed around HWPP mesh can be managed similarly to MWPP mesh.</description><subject>Abdominal Surgery</subject><subject>Hernia</subject><subject>Hernias</subject><subject>Inflammation</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Morbidity</subject><subject>Original</subject><subject>Original Article</subject><subject>Polypropylene</subject><subject>Wounds</subject><issn>1248-9204</issn><issn>1265-4906</issn><issn>1248-9204</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><recordid>eNp9UcuOFCEUrRiN89AfcGFI3Lgp5VUFrMxkoo7JJG50TW7TVDcTCkooelIfM_8qY7Xj6MIFcMN5cMhpmlcEvyMYi_e57lS1mPK6lKCteNKcEsplqyjmTx_NJ81ZzjcYY8l7-bw5YZJj1Qly2txdBPBLdhnFASU7pziWbIqHhLYJXECxzFOZEYQtmmKe42QTzO5g7wETR5vREBPaWzgst9bt9jM62JRLRqPdujIe76bolynFafE22ArlfZV5H29d2KHqGaoqzAl8dUrBQY0ygUsvmmcD-GxfHs_z5vunj98ur9rrr5-_XF5ct4bTfm7FBqQykkmgfb8FMvRU9IYCMUQNG0sV9MJyY9imU2ywjNJO9qaThDCuoAN23nxYfaeyqbnNmkVPyY2QFh3B6b-R4PZ6Fw-aYKVEL3F1eHt0SPFHsXnWo8vGeg_BxpI1VYxyRhXhlfrmH-pNLKnWkDXDjIlOMqwqi64sk2LOyQ4PaQjW9_XrtX5d69e_6teiil4__seD5HfflcBWQq5Q2Nn05-3_2P4EooTBMQ</recordid><startdate>20240401</startdate><enddate>20240401</enddate><creator>Essani, V.</creator><creator>Maskal, S. M.</creator><creator>Ellis, R. C.</creator><creator>Messer, N.</creator><creator>Tu, C.</creator><creator>Miller, B. T.</creator><creator>Petro, C. C.</creator><creator>Beffa, L. R. A.</creator><creator>Krpata, D. M.</creator><creator>Prabhu, A. S.</creator><creator>Rosen, M. J.</creator><general>Springer Paris</general><general>Springer Nature B.V</general><scope>C6C</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-7072-1944</orcidid></search><sort><creationdate>20240401</creationdate><title>Analysis of retromuscular drain output and postoperative outcomes for heavyweight versus mediumweight polypropylene mesh following open ventral hernia repair</title><author>Essani, V. ; Maskal, S. M. ; Ellis, R. C. ; Messer, N. ; Tu, C. ; Miller, B. T. ; Petro, C. C. ; Beffa, L. R. A. ; Krpata, D. M. ; Prabhu, A. S. ; Rosen, M. J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c426t-7ba89c838a266da1f6276c2a1c19fbe29a67e4cc3b593fe322586c5811349a5a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Abdominal Surgery</topic><topic>Hernia</topic><topic>Hernias</topic><topic>Inflammation</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Morbidity</topic><topic>Original</topic><topic>Original Article</topic><topic>Polypropylene</topic><topic>Wounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Essani, V.</creatorcontrib><creatorcontrib>Maskal, S. M.</creatorcontrib><creatorcontrib>Ellis, R. C.</creatorcontrib><creatorcontrib>Messer, N.</creatorcontrib><creatorcontrib>Tu, C.</creatorcontrib><creatorcontrib>Miller, B. T.</creatorcontrib><creatorcontrib>Petro, C. C.</creatorcontrib><creatorcontrib>Beffa, L. R. A.</creatorcontrib><creatorcontrib>Krpata, D. M.</creatorcontrib><creatorcontrib>Prabhu, A. S.</creatorcontrib><creatorcontrib>Rosen, M. J.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Hernia : the journal of hernias and abdominal wall surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Essani, V.</au><au>Maskal, S. M.</au><au>Ellis, R. C.</au><au>Messer, N.</au><au>Tu, C.</au><au>Miller, B. T.</au><au>Petro, C. C.</au><au>Beffa, L. R. A.</au><au>Krpata, D. M.</au><au>Prabhu, A. S.</au><au>Rosen, M. J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of retromuscular drain output and postoperative outcomes for heavyweight versus mediumweight polypropylene mesh following open ventral hernia repair</atitle><jtitle>Hernia : the journal of hernias and abdominal wall surgery</jtitle><stitle>Hernia</stitle><addtitle>Hernia</addtitle><date>2024-04-01</date><risdate>2024</risdate><volume>28</volume><issue>2</issue><spage>637</spage><epage>642</epage><pages>637-642</pages><issn>1248-9204</issn><issn>1265-4906</issn><eissn>1248-9204</eissn><abstract>Purpose
Heavyweight polypropylene (HWPP) mesh is thought to increase inflammatory response and delay tissue integration compared to mediumweight (MWPP). Reactive fluid volume (i.e., drain output) may be a reasonable surrogate for integration. We hypothesized that daily drain output is higher with HWPP compared to MWPP in open retromuscular ventral hernia repair (VHR).
Methods
This is a post-hoc analysis of a multicenter, randomized clinical trial conducted March 2017–April 2019 comparing MWPP and HWPP for VHR. Retromuscular drain output in milliliters was measured at 24-h intervals up to postoperative day seven. Univariate analyses compared differences in daily drain output and time to drain removal. Multivariable analyses compared total drain output and wound morbidity within 30 days and hernia recurrence at 1 year.
Results
288 patients were included; 140 (48.6%) HWPP and 148 (51.4%) MWPP. Daily drain output for days 1–3 was higher for HWPP vs. MWPP (total volume: 837.8 mL vs. 656.5 mL) (
p
< 0.001), but similar on days 4–7 (
p
> 0.05). Median drain removal time was 5 days for both groups. Total drain output was not predictive of 30-day wound morbidity (
p
> 0.05) or hernia recurrence at 1 year (OR 1,
p
= 0.29).
Conclusion
While HWPP mesh initially had higher drain outputs, it rapidly returned to levels similar to MWPP by postoperative day three and there was no difference in clinical outcomes. We believe that drains placed around HWPP mesh can be managed similarly to MWPP mesh.</abstract><cop>Paris</cop><pub>Springer Paris</pub><pmid>38409571</pmid><doi>10.1007/s10029-024-02972-7</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0001-7072-1944</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1248-9204 |
| ispartof | Hernia : the journal of hernias and abdominal wall surgery, 2024-04, Vol.28 (2), p.637-642 |
| issn | 1248-9204 1265-4906 1248-9204 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_10997680 |
| source | Springer Nature:Jisc Collections:Springer Nature Read and Publish 2023-2025: Springer Reading List |
| subjects | Abdominal Surgery Hernia Hernias Inflammation Medicine Medicine & Public Health Morbidity Original Original Article Polypropylene Wounds |
| title | Analysis of retromuscular drain output and postoperative outcomes for heavyweight versus mediumweight polypropylene mesh following open ventral hernia repair |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T03%3A16%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Analysis%20of%20retromuscular%20drain%20output%20and%20postoperative%20outcomes%20for%20heavyweight%20versus%20mediumweight%20polypropylene%20mesh%20following%20open%20ventral%20hernia%20repair&rft.jtitle=Hernia%20:%20the%20journal%20of%20hernias%20and%20abdominal%20wall%20surgery&rft.au=Essani,%20V.&rft.date=2024-04-01&rft.volume=28&rft.issue=2&rft.spage=637&rft.epage=642&rft.pages=637-642&rft.issn=1248-9204&rft.eissn=1248-9204&rft_id=info:doi/10.1007/s10029-024-02972-7&rft_dat=%3Cproquest_pubme%3E2932432914%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c426t-7ba89c838a266da1f6276c2a1c19fbe29a67e4cc3b593fe322586c5811349a5a3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=3033758309&rft_id=info:pmid/38409571&rfr_iscdi=true |