Antineutrophilic Cytoplasmic Antibody-Related Spinal Pachymeningitis

Isolated spinal pachymeningitis is rarely encountered in clinical practice. Narrowing down the specific cause in individual patients is challenging as the possible etiologies are broad, there is substantial overlap in clinical presentation, and obtaining adequate data is complex, often affected by p...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-03, Vol.16 (3), p.e55963
Main Authors: Gritti, Linda, Carabenciov, Ivan, Diehn, Felix, Trejo-Lopez, Jorge A, Martinez-Thompson, Jennifer M, Lanzino, Giuseppe
Format: Article
Language:English
Subjects:
Antibodies
Back pain
Biopsy
Blood products
Cardiovascular disease
Coronary vessels
Epidural
Epistaxis
Granulomas
Internal Medicine
Lymphocytes
Neurology
Pacemakers
Rheumatology
Spinal cord
Tomography
Vein & artery diseases
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Summary:Isolated spinal pachymeningitis is rarely encountered in clinical practice. Narrowing down the specific cause in individual patients is challenging as the possible etiologies are broad, there is substantial overlap in clinical presentation, and obtaining adequate data is complex, often affected by prior empiric treatments, including steroids. Here, we describe a rare patient with spinal pachymeningitis resulting in subacute to chronic progressive lower extremity weakness and eventually paraplegia. We discuss how we obtained the final diagnosis, provide our diagnostic framework, and offer practical advice in evaluating these patients.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.55963