Effect of exogenous bile salts supplementation on the performance and hepatic lipid metabolism of aged laying hens

Abstract Bile acids (BA), a series of hydroxylated steroids secreted by the liver, are involved in the digestion and absorption of dietary fats. In the present study, the effect of exogenous BAs on the performance and liver lipid metabolism of laying hens was investigated. Three hundred and sixty 50...

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Bibliographic Details
Published in:Journal of animal science 2023-01, Vol.101
Main Authors: Sun, Lijing, Xin, Qian, Jiao, Hongchao, Wang, Xiaojuan, Zhao, Jingpeng, Li, Haifang, Zhou, Yunlei, Cao, Aizhi, Wang, Jianmin, Lin, Hai
Format: Article
Language:English
Subjects:
Accumulation
Acetyl-CoA carboxylase
Animal Feed - analysis
Animals
Apolipoprotein B
Bile acids
Bile Acids and Salts - metabolism
Chickens - metabolism
Color
Cytochrome
Cytochrome P450
Cytochromes P450
Diet
Diet - veterinary
Dietary Fats - pharmacology
Dietary Supplements
Duodenum
Egg shells
Eggs
Fatty Acid Synthases
Fatty acids
Fatty-acid synthase
Feed conversion
Feed efficiency
Feeds
Female
Gene expression
Genes
Jejunum
Lipid Metabolism
Lipids
Liver
Liver - metabolism
Low density lipoprotein
Low density lipoprotein receptors
Metabolism
Mortality
Ovum - metabolism
Poultry
Receptor density
Receptors
Steroid hormones
Sterol regulatory element-binding protein
Swine
Yolk
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Summary:Abstract Bile acids (BA), a series of hydroxylated steroids secreted by the liver, are involved in the digestion and absorption of dietary fats. In the present study, the effect of exogenous BAs on the performance and liver lipid metabolism of laying hens was investigated. Three hundred and sixty 50-wk-old Hy-line Brown hens were randomly allocated into three groups and subjected to one of the following treatments: fed with the basal diet (control, Con), the basal diet supplemented with 0.1 g/kg (0.1 g/kg BAs), or 0.2 g/kg (0.2 g/kg BAs) porcine BAs. Laying performance, egg quality, and blood parameters were measured during the 8-wk experimental period. The expression of genes related to hepatic lipid metabolism was determined at the end of experiment. The results showed that BAs treatments had no influence (P > 0.05) on laying rate, egg weight, and feed efficiency. BAs treatment, however, significantly decreased mortality of hens (P = 0.006). BAs treatment showed a transient negative influence on eggshell quality at week 4 but not at week 8. The yolk color on week 8 was increased by BAs treatments (P 
ISSN:0021-8812
1525-3163
1525-3163
DOI:10.1093/jas/skad334