Adverse pathologic features impact survival outcomes for small renal masses following nephrectomy

•The impact of adverse pathologic pT3a features on small renal masses is unclear.•We compared clinical outcomes of pT3a vs pT1 small renal masses at our institution.•9.04% of resected malignant small renal masses were deemed pT3a post-operatively.•Small pT3a masses had worse recurrence-free and canc...

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Published in:Urologic oncology 2023-09, Vol.41 (9), p.391.e5-391.e11
Main Authors: Khaleel, Sari, Truong, Hong, Jiang, Song, K-Lee, Paul, Davelman, Benjamin, Gordon, Danielle, Benfante, Nicole, Arora, Arshi, Ostrovnaya, Irina, Tickoo, Satish, Coleman, Jonathan, Hakimi, A. Ari, Russo, Paul
Format: Article
Language:English
Subjects:
Adverse pathology
Carcinoma, Renal Cell - pathology
Humans
Kidney Neoplasms - pathology
Neoplasm Staging
Nephrectomy - methods
Retrospective Studies
Small renal mass
T3 stage
T3a stage
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Summary:•The impact of adverse pathologic pT3a features on small renal masses is unclear.•We compared clinical outcomes of pT3a vs pT1 small renal masses at our institution.•9.04% of resected malignant small renal masses were deemed pT3a post-operatively.•Small pT3a masses had worse recurrence-free and cancer-specific survival.•pT3a stage portends worse clinical outcomes even for small renal masses. While most small renal masses (SRM) < 4 cm have an excellent prognosis following resection, the impact of adverse T3a pathologic features on oncologic outcomes of SRMs remains unclear. We sought to compare clinical outcomes for surgically resected pT3a versus pT1a SRMs at our institution. We retrospectively reviewed records of patients who underwent radical or partial nephrectomy (RN, PN) for renal tumors
ISSN:1078-1439
1873-2496
1873-2496
DOI:10.1016/j.urolonc.2023.06.010