Trends in the prevalence and incidence of Crohn’s disease in Japan and the United States

Purpose This study is to describe patient demographic characteristics and estimate annual prevalence and incidence rates of Crohn’s disease (CD) in Japan and the United States (US). Methods Two large employment-based healthcare claims databases (Japan Medical Data Center [JMDC] in Japan and Merative...

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Bibliographic Details
Published in:International journal of colorectal disease 2024-04, Vol.39 (1), p.61-61, Article 61
Main Authors: Nakajo, Ko, Yamazaki, Michiyo, Chung, Hsingwen, Xu, Youran, Qiu, Hong
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Child
Crohn Disease - epidemiology
Female
Gastroenterology
Hepatology
Humans
Incidence
Internal Medicine
Japan - epidemiology
Male
Medicine
Medicine & Public Health
Middle Aged
Prevalence
Proctology
Surgery
United States - epidemiology
Young Adult
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Summary:Purpose This study is to describe patient demographic characteristics and estimate annual prevalence and incidence rates of Crohn’s disease (CD) in Japan and the United States (US). Methods Two large employment-based healthcare claims databases (Japan Medical Data Center [JMDC] in Japan and Merative MarketScan [Merative] in the US) were used to identify patients with CD from 2010 to 2019. Cases were confirmed using an algorithm based on diagnostic with/without treatment codes. The Merative population was used for sex and age standardization of annual prevalence and incidence rates estimated from the JMDC. Results Patients with CD were generally younger in Japan than in the US at diagnosis (mean 33.6 vs. 39.4 years) and 71.5% were male versus 45.1% in the US. Annual prevalence per 100,000 population increased substantially in both countries, from 34.2 in 2010 to 54.5 in 2019 in Japan (standardized) and 163.3 to 224.2 in the US. Prevalence rates increased in both males and females in all age groups between 6 and 
ISSN:1432-1262
0179-1958
1432-1262
DOI:10.1007/s00384-024-04636-5