Proteomics in Psoriasis: Recent Advances

Psoriasis continues to affect a large percentage of patients worldwide and strongly appears to be a systematic disease. Efforts are being made to understand its etiology, which have led to research extended to genomic analysis with a focus on the role of pro-inflammatory cytokines, which play a majo...

Full description

Saved in:
Bibliographic Details
Published in:In vivo (Athens) 2024-05, Vol.38 (3), p.1000-1008
Main Authors: Leotsakos, Georgios, Katafigiotis, Ioannis, Leotsakos, Ioannis, Kousta, Fiori, Molympakis, Aristeidis, Perimeni, Aikaterini, Koutsilieris, Michael
Format: Article
Language:English
Subjects:
Biomarkers
Cytokines - blood
Cytokines - metabolism
Humans
Prognosis
Proteome - metabolism
Proteomics - methods
Psoriasis - blood
Psoriasis - genetics
Psoriasis - metabolism
Review
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Psoriasis continues to affect a large percentage of patients worldwide and strongly appears to be a systematic disease. Efforts are being made to understand its etiology, which have led to research extended to genomic analysis with a focus on the role of pro-inflammatory cytokines, which play a major role in the pathogenesis of the disease. Plasma proteomic analysis in various diseases has provided promising results for choosing the right treatment for psoriasis, suggesting that it could play a key role in the prevention, prognosis, and treatment of the disease by individualizing treatment choices based on the proteomic profile of each patient. In this review, we focus on existing data in the bibliography on proteomic analysis in psoriasis and relevant approaches to future targeted therapies.
ISSN:0258-851X
1791-7549
DOI:10.21873/invivo.13533