Loading…
Emerging strategies for cancer immunoprevention
The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammat...
Saved in:
| Published in: | Oncogene 2015-12, Vol.34 (50), p.6029-6039 |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3 |
| container_end_page | 6039 |
| container_issue | 50 |
| container_start_page | 6029 |
| container_title | Oncogene |
| container_volume | 34 |
| creator | Roeser, J C Leach, S D McAllister, F |
| description | The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis. |
| doi_str_mv | 10.1038/onc.2015.98 |
| format | article |
| fullrecord | <record><control><sourceid>gale_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11073473</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A437224604</galeid><sourcerecordid>A437224604</sourcerecordid><originalsourceid>FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3</originalsourceid><addsrcrecordid>eNqNkstrFTEUxoMo9ra6ci8X3Ah1bvN-rKSU-oCCG12H3Ewypswk12Sm4H_vudxaWykiWQRyfvnOOR8fQq8I3hDM9FnJfkMxERujn6AV4Up2Qhj-FK2wEbgzlNEjdNzaNcZYGUyfoyMqmeSSiBU6u5xCHVIe1m2ubg5DCm0dS117l32o6zRNSy67Gm5CnlPJL9Cz6MYWXt7eJ-jbh8uvF5-6qy8fP1-cX3VecjF3W0mMovt2XjkiiHZc8KiiNAYA17tIldOmh5GcizJgRSVVMuot7o0Onp2g9wfd3bKdQu-he3Wj3dU0ufrTFpfsw0pO3-1QbiwhWDGuGCi8vVWo5ccS2myn1HwYR5dDWZolSoJLnGjzHyg3kmKhBKBv_kKvy1IzWGEpY0QSqaX6FwVaMB9THP-hBjcGm3IssInft7bnQFDKJeZAbR6h4PRhSr7kEBO8P_hwevjga2mthnjnGsF2nxgLibH7xFijgX593-g79ndEAHh3ABqU8hDqvV0e0fsFMMPHHQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1747343740</pqid></control><display><type>article</type><title>Emerging strategies for cancer immunoprevention</title><source>Springer Nature</source><creator>Roeser, J C ; Leach, S D ; McAllister, F</creator><creatorcontrib>Roeser, J C ; Leach, S D ; McAllister, F</creatorcontrib><description>The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.</description><identifier>ISSN: 0950-9232</identifier><identifier>EISSN: 1476-5594</identifier><identifier>DOI: 10.1038/onc.2015.98</identifier><identifier>PMID: 26364615</identifier><identifier>CODEN: ONCNES</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>631/250/256 ; Apoptosis ; Cancer ; Cell Biology ; Chemoprevention ; Dendritic Cells - immunology ; Human Genetics ; Humans ; Immune system ; Immunotherapy ; Interleukin 1 Receptor Antagonist Protein - physiology ; Interleukin-6 - antagonists & inhibitors ; Interleukin-8 - antagonists & inhibitors ; Internal Medicine ; Medicine ; Medicine & Public Health ; Methods ; Monitoring, Immunologic ; Neoplasms - immunology ; Neoplasms - prevention & control ; Oncology ; Oncology, Experimental ; Prevention ; Programmed Cell Death 1 Receptor - physiology ; review ; STAT3 Transcription Factor - antagonists & inhibitors ; T-Lymphocytes, Regulatory - immunology ; Th17 Cells - immunology ; Tumorigenesis ; Tumors ; Vaccines</subject><ispartof>Oncogene, 2015-12, Vol.34 (50), p.6029-6039</ispartof><rights>Macmillan Publishers Limited 2015</rights><rights>COPYRIGHT 2015 Nature Publishing Group</rights><rights>Copyright Nature Publishing Group Dec 10, 2015</rights><rights>Macmillan Publishers Limited 2015.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3</citedby><cites>FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>230,314,777,781,882,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26364615$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Roeser, J C</creatorcontrib><creatorcontrib>Leach, S D</creatorcontrib><creatorcontrib>McAllister, F</creatorcontrib><title>Emerging strategies for cancer immunoprevention</title><title>Oncogene</title><addtitle>Oncogene</addtitle><addtitle>Oncogene</addtitle><description>The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.</description><subject>631/250/256</subject><subject>Apoptosis</subject><subject>Cancer</subject><subject>Cell Biology</subject><subject>Chemoprevention</subject><subject>Dendritic Cells - immunology</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Immune system</subject><subject>Immunotherapy</subject><subject>Interleukin 1 Receptor Antagonist Protein - physiology</subject><subject>Interleukin-6 - antagonists & inhibitors</subject><subject>Interleukin-8 - antagonists & inhibitors</subject><subject>Internal Medicine</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Methods</subject><subject>Monitoring, Immunologic</subject><subject>Neoplasms - immunology</subject><subject>Neoplasms - prevention & control</subject><subject>Oncology</subject><subject>Oncology, Experimental</subject><subject>Prevention</subject><subject>Programmed Cell Death 1 Receptor - physiology</subject><subject>review</subject><subject>STAT3 Transcription Factor - antagonists & inhibitors</subject><subject>T-Lymphocytes, Regulatory - immunology</subject><subject>Th17 Cells - immunology</subject><subject>Tumorigenesis</subject><subject>Tumors</subject><subject>Vaccines</subject><issn>0950-9232</issn><issn>1476-5594</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqNkstrFTEUxoMo9ra6ci8X3Ah1bvN-rKSU-oCCG12H3Ewypswk12Sm4H_vudxaWykiWQRyfvnOOR8fQq8I3hDM9FnJfkMxERujn6AV4Up2Qhj-FK2wEbgzlNEjdNzaNcZYGUyfoyMqmeSSiBU6u5xCHVIe1m2ubg5DCm0dS117l32o6zRNSy67Gm5CnlPJL9Cz6MYWXt7eJ-jbh8uvF5-6qy8fP1-cX3VecjF3W0mMovt2XjkiiHZc8KiiNAYA17tIldOmh5GcizJgRSVVMuot7o0Onp2g9wfd3bKdQu-he3Wj3dU0ufrTFpfsw0pO3-1QbiwhWDGuGCi8vVWo5ccS2myn1HwYR5dDWZolSoJLnGjzHyg3kmKhBKBv_kKvy1IzWGEpY0QSqaX6FwVaMB9THP-hBjcGm3IssInft7bnQFDKJeZAbR6h4PRhSr7kEBO8P_hwevjga2mthnjnGsF2nxgLibH7xFijgX593-g79ndEAHh3ABqU8hDqvV0e0fsFMMPHHQ</recordid><startdate>20151210</startdate><enddate>20151210</enddate><creator>Roeser, J C</creator><creator>Leach, S D</creator><creator>McAllister, F</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope></search><sort><creationdate>20151210</creationdate><title>Emerging strategies for cancer immunoprevention</title><author>Roeser, J C ; Leach, S D ; McAllister, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>631/250/256</topic><topic>Apoptosis</topic><topic>Cancer</topic><topic>Cell Biology</topic><topic>Chemoprevention</topic><topic>Dendritic Cells - immunology</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>Immune system</topic><topic>Immunotherapy</topic><topic>Interleukin 1 Receptor Antagonist Protein - physiology</topic><topic>Interleukin-6 - antagonists & inhibitors</topic><topic>Interleukin-8 - antagonists & inhibitors</topic><topic>Internal Medicine</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Methods</topic><topic>Monitoring, Immunologic</topic><topic>Neoplasms - immunology</topic><topic>Neoplasms - prevention & control</topic><topic>Oncology</topic><topic>Oncology, Experimental</topic><topic>Prevention</topic><topic>Programmed Cell Death 1 Receptor - physiology</topic><topic>review</topic><topic>STAT3 Transcription Factor - antagonists & inhibitors</topic><topic>T-Lymphocytes, Regulatory - immunology</topic><topic>Th17 Cells - immunology</topic><topic>Tumorigenesis</topic><topic>Tumors</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Roeser, J C</creatorcontrib><creatorcontrib>Leach, S D</creatorcontrib><creatorcontrib>McAllister, F</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biological Sciences</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Oncogene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Roeser, J C</au><au>Leach, S D</au><au>McAllister, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Emerging strategies for cancer immunoprevention</atitle><jtitle>Oncogene</jtitle><stitle>Oncogene</stitle><addtitle>Oncogene</addtitle><date>2015-12-10</date><risdate>2015</risdate><volume>34</volume><issue>50</issue><spage>6029</spage><epage>6039</epage><pages>6029-6039</pages><issn>0950-9232</issn><eissn>1476-5594</eissn><coden>ONCNES</coden><abstract>The crucial role of the immune system in the formation and progression of tumors has been widely accepted. On one hand, the surveillance role of the immune system plays an important role in endogenous tumor prevention, but on the other hand, in some special circumstances such as in chronic inflammation, the immune system can actually contribute to the formation and progression of tumors. In recent years, there has been an explosion of novel targeted immunotherapies for advanced cancers. In the present manuscript, we explore known and potential various types of cancer prevention strategies and focus on nonvaccine-based cancer preventive strategies targeting the immune system at the early stages of tumorigenesis.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>26364615</pmid><doi>10.1038/onc.2015.98</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0950-9232 |
| ispartof | Oncogene, 2015-12, Vol.34 (50), p.6029-6039 |
| issn | 0950-9232 1476-5594 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_11073473 |
| source | Springer Nature |
| subjects | 631/250/256 Apoptosis Cancer Cell Biology Chemoprevention Dendritic Cells - immunology Human Genetics Humans Immune system Immunotherapy Interleukin 1 Receptor Antagonist Protein - physiology Interleukin-6 - antagonists & inhibitors Interleukin-8 - antagonists & inhibitors Internal Medicine Medicine Medicine & Public Health Methods Monitoring, Immunologic Neoplasms - immunology Neoplasms - prevention & control Oncology Oncology, Experimental Prevention Programmed Cell Death 1 Receptor - physiology review STAT3 Transcription Factor - antagonists & inhibitors T-Lymphocytes, Regulatory - immunology Th17 Cells - immunology Tumorigenesis Tumors Vaccines |
| title | Emerging strategies for cancer immunoprevention |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T22%3A02%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Emerging%20strategies%20for%20cancer%20immunoprevention&rft.jtitle=Oncogene&rft.au=Roeser,%20J%20C&rft.date=2015-12-10&rft.volume=34&rft.issue=50&rft.spage=6029&rft.epage=6039&rft.pages=6029-6039&rft.issn=0950-9232&rft.eissn=1476-5594&rft.coden=ONCNES&rft_id=info:doi/10.1038/onc.2015.98&rft_dat=%3Cgale_pubme%3EA437224604%3C/gale_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c645t-b619720790c7a1518a454f7f699c64adaf27a89d000aaf6e0726276f8b0d98ec3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=1747343740&rft_id=info:pmid/26364615&rft_galeid=A437224604&rfr_iscdi=true |