Mesenchymal stem cells from preterm to term newborns undergo a significant switch from anaerobic glycolysis to the oxidative phosphorylation

We evaluated the energy metabolism of human mesenchymal stem cells (MSC) isolated from umbilical cord (UC) of preterm (

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Bibliographic Details
Published in:Cellular and molecular life sciences : CMLS 2018-03, Vol.75 (5), p.889-903
Main Authors: Ravera, Silvia, Podestà, Marina, Sabatini, Federica, Fresia, Chiara, Columbaro, Marta, Bruno, Silvia, Fulcheri, Ezio, Ramenghi, Luca Antonio, Frassoni, Francesco
Format: Article
Language:English
Subjects:
Age
Anaerobiosis
Biochemistry
Biomedical and Life Sciences
Biomedicine
Births
Bone marrow
Cell Biology
Cells, Cultured
Energy metabolism
Energy Metabolism - physiology
Fetuses
Gene expression
Gestational age
Glycolysis
Glycolysis - physiology
Humans
Infant, Newborn
Infant, Premature
Information management
Life Sciences
Mesenchymal stem cells
Mesenchymal Stem Cells - cytology
Mesenchymal Stem Cells - metabolism
Mesenchyme
Metabolism
Mitochondria
mRNA
Neonates
Original
Original Article
Oxidative Phosphorylation
Oxidative stress
Phosphorylation
Premature birth
Premature Birth - metabolism
Proteins
Ribonucleic acid
RNA
RNA-binding protein
Stem cells
Term Birth - metabolism
Umbilical cord
Umbilical Cord - cytology
Umbilical Cord - metabolism
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Description
Summary:We evaluated the energy metabolism of human mesenchymal stem cells (MSC) isolated from umbilical cord (UC) of preterm (
ISSN:1420-682X
1420-9071
DOI:10.1007/s00018-017-2665-z