Auto-brewery syndrome in a 50-year-old woman

Auto-brewery syndrome is a rare syndrome of endogenous alcohol fermentation. It is thought to result when microorganisms capable of fermenting alcohol from carbohydrates outgrow normal gut flora. Although population-based studies have shown that gut alcohol fermentation with low levels of endogenous...

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Bibliographic Details
Published in:Canadian Medical Association journal (CMAJ) 2024-06, Vol.196 (21), p.E724-E727
Main Authors: Zewude, Rahel T., MD, Croitoru, Kenneth, MD, Goldman, Brian, MD, Bogoch, Isaac I., MD, Das, Ronit, MD
Format: Article
Language:English
Subjects:
Alcohol use
Alcohol-related disorders
Alcoholism
Antibiotics
Bacteria
Breweries
Brewing industry
Carbohydrates
Case studies
Colonoscopy
Diet
Dietitians
Drunkenness
Dysbiosis
Emergency medical care
Enzymes
Ethanol
Fermentation
Fungi
Gastroenterology
Glucose
Health aspects
Infectious diseases
Internal Medicine
Intoxication
Metabolism
Microbiota
Microorganisms
Patients
Practice
Probiotics
Questionnaires
Urinary tract infections
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Summary:Auto-brewery syndrome is a rare syndrome of endogenous alcohol fermentation. It is thought to result when microorganisms capable of fermenting alcohol from carbohydrates outgrow normal gut flora. Although population-based studies have shown that gut alcohol fermentation with low levels of endogenous ethanol can occur even among healthy people, blood ethanol levels rarely reach concentrations high enough to cause intoxication. Auto-brewery syndrome is uncommon because it requires several host factors to interact with substantial overpopulation of fermenting microorganisms, and high carbohydrate consumption. Here, Zewude et al examine the case of a 50-year-old woman with auto-brewery syndrome.
ISSN:0820-3946
1488-2329
1488-2329
DOI:10.1503/cmaj.231319