Clinical Outcomes of Medial Meniscal Allograft Transplantation With or Without High Tibial Osteotomy: A Case-Control Study Up to 8 Years of Follow-up

Background: Satisfactory clinical results of meniscal allograft transplantation (MAT) have been reported in recent years. However, it remains unclear whether the clinical outcomes of MAT when combined with an osteotomy are inferior to those of isolated MAT. Purpose: To compare the survival rates and...

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Published in:The American journal of sports medicine 2024-06, Vol.52 (7), p.1813-1819
Main Authors: Grassi, Alberto, Lucidi, Gian Andrea, Di Paolo, Stefano, Altovino, Emanuele, Agostinone, Piero, Dal Fabbro, Giacomo, Romandini, Iacopo, Filardo, Giuseppe, Zaffagnini, Stefano
Format: Article
Language:English
Subjects:
Adult
Allografts
Arthroscopy
Case-Control Studies
Clinical outcomes
Female
Follow-Up Studies
Humans
Male
Menisci, Tibial - surgery
Menisci, Tibial - transplantation
Middle Aged
Osteotomy - methods
Reoperation - statistics & numerical data
Tibia - surgery
Tibia - transplantation
Transplantation, Homologous
Treatment Outcome
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Summary:Background: Satisfactory clinical results of meniscal allograft transplantation (MAT) have been reported in recent years. However, it remains unclear whether the clinical outcomes of MAT when combined with an osteotomy are inferior to those of isolated MAT. Purpose: To compare the survival rates and clinical outcomes of patients who received isolated medial MAT with those of patients undergoing medial MAT combined with high tibial osteotomy (HTO). Study Design: Cohort study; Level of evidence, 3. Methods: A total of 55 patients underwent arthroscopic medial MAT using the soft tissue technique and HTO (mean age, 41.3 ± 10.4 years; 9 female); after fuzzy case-control matching on demographics, 55 controls who underwent isolated medial MAT were also included. Survival analyses were performed using the Kaplan-Meier method with surgical failure, clinical failure (Lysholm score, .05). At the final follow-up, 8 of 55 (14.5%) of the MAT + HTO patients and 9 of 55 (16.4%) of the MAT patients had a Lysholm score .05). Conclusion: Patients undergoing medial MAT + HTO showed similar clinical results to patients undergoing isolated medial MAT at midterm follow-up, and thus a surgically addressed malalignment does not represent a contraindication for medial MAT. However, the need for a concomitant HTO is associated with a slightly higher failure rate over time.
ISSN:0363-5465
1552-3365
1552-3365
DOI:10.1177/03635465241248822