Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies

Prostate cancer lung metastasis represents a clinical conundrum due to its implications for advanced disease progression and the complexities it introduces in treatment planning. As the disease progresses to distant sites such as the lung, the clinical management becomes increasingly intricate, requ...

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Bibliographic Details
Published in:Cancers 2024-05, Vol.16 (11), p.2080
Main Authors: Mahmoud, Ahmed M, Moustafa, Amr, Day, Carter, Ahmed, Mohamed E, Zeina, Wael, Marzouk, Usama M, Basourakos, Spyridon, Haloi, Rimki, Mahon, Mindie, Muniz, Miguel, Childs, Daniel S, Orme, Jacob J, Riaz, Irbaz Bin, Kendi, A Tuba, Stish, Bradley J, Davis, Brian J, Kwon, Eugene D, Andrews, Jack R
Format: Article
Language:English
Subjects:
Asymptomatic
Bones
Care and treatment
Chemotherapy
Development and progression
Diagnosis
Dyspnea
Hemoptysis
Lung cancer
Lungs
Magnetic resonance imaging
Medical imaging
Medical prognosis
Metastases
Metastasis
Patients
Prostate cancer
Radiation therapy
Review
Surgery
Therapeutic applications
Tomography
X-rays
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Summary:Prostate cancer lung metastasis represents a clinical conundrum due to its implications for advanced disease progression and the complexities it introduces in treatment planning. As the disease progresses to distant sites such as the lung, the clinical management becomes increasingly intricate, requiring tailored therapeutic strategies to address the unique characteristics of metastatic lesions. This review seeks to synthesize the current state of knowledge surrounding prostate cancer metastasis to the lung, shedding light on the diverse array of clinical presentations encountered, ranging from subtle radiological findings to overt symptomatic manifestations. By examining the diagnostic modalities utilized in identifying this metastasis, including advanced imaging techniques and histopathological analyses, this review aims to provide insights into the diagnostic landscape and the challenges associated with accurately characterizing lung metastatic lesions in prostate cancer patients. Moreover, this review delves into the nuances of therapeutic interventions employed in managing prostate cancer lung metastasis, encompassing systemic treatments such as hormonal therapies and chemotherapy, as well as metastasis-directed therapies including surgery and radiotherapy.
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers16112080