Stereotactic Body Radiotherapy in Recurrent and Oligometastatic Head and Neck Tumours

The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional ra...

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Bibliographic Details
Published in:Journal of clinical medicine 2024-06, Vol.13 (11), p.3020
Main Authors: Tham, Jodie L M, Ng, Sweet Ping, Khor, Richard, Wada, Morikatsu, Gan, Hui, Thai, Alesha A, Corry, June, Bahig, Houda, Mäkitie, Antti A, Nuyts, Sandra, De Bree, Remco, Strojan, Primož, Ng, Wai Tong, Eisbruch, Avraham, Chow, James C H, Ferlito, Alfio
Format: Article
Language:English
Subjects:
Cancer therapies
Care and treatment
Chemotherapy
Head & neck cancer
Medical prognosis
Metastasis
Patients
Radiation therapy
Radiotherapy
Review
Surgery
Toxicity
Tumors
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Summary:The treatment of head and neck cancers (HNCs) encompasses a complex paradigm involving a combination of surgery, radiotherapy, and systemic treatment. Locoregional recurrence is a common cause of treatment failure, and few patients are suitable for salvage surgery. Reirradiation with conventional radiation techniques is challenging due to normal tissue tolerance limits and the risk of significant toxicities. Stereotactic body radiotherapy (SBRT) has emerged as a highly conformal modality that offers the potential for cure while limiting the dose to surrounding tissue. There is also growing research that shows that those with oligometastatic disease can benefit from curative intent local ablative therapies such as SBRT. This review will look at published evidence regarding the use of SBRT in locoregional recurrent and oligometastatic HNCs.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm13113020