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Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study

ObjectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid...

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Published in:Occupational and environmental medicine (London, England) England), 2024-05, Vol.81 (5), p.245-251
Main Authors: Mathieson, Stephanie, Collie, Alex, Maher, Christopher G, Abdel Shaheed, Christina, Xia, Ting, Gilbert, Stephen, Ferreira, Giovanni E, Di Donato, Michael F
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container_title Occupational and environmental medicine (London, England)
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creator Mathieson, Stephanie
Collie, Alex
Maher, Christopher G
Abdel Shaheed, Christina
Xia, Ting
Gilbert, Stephen
Ferreira, Giovanni E
Di Donato, Michael F
description ObjectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.
doi_str_mv 10.1136/oemed-2023-109369
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To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.</description><identifier>ISSN: 1351-0711</identifier><identifier>ISSN: 1470-7926</identifier><identifier>EISSN: 1470-7926</identifier><identifier>DOI: 10.1136/oemed-2023-109369</identifier><identifier>PMID: 38782576</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Age groups ; Analgesics ; Antidepressants ; Back injuries ; Back Pain ; Dispensing ; Expenditures ; Health services research ; Injury analysis ; Low back pain ; Missing data ; Narcotics ; Pain ; Pain management ; Reimbursement ; Socioeconomic factors ; Socioeconomic status ; Trends ; Variables ; Veterans ; Workers ; Workers compensation ; Workplace</subject><ispartof>Occupational and environmental medicine (London, England), 2024-05, Vol.81 (5), p.245-251</ispartof><rights>Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ.</rights><rights>2024 Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. 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To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.</description><subject>Age groups</subject><subject>Analgesics</subject><subject>Antidepressants</subject><subject>Back injuries</subject><subject>Back Pain</subject><subject>Dispensing</subject><subject>Expenditures</subject><subject>Health services research</subject><subject>Injury analysis</subject><subject>Low back pain</subject><subject>Missing data</subject><subject>Narcotics</subject><subject>Pain</subject><subject>Pain management</subject><subject>Reimbursement</subject><subject>Socioeconomic factors</subject><subject>Socioeconomic status</subject><subject>Trends</subject><subject>Variables</subject><subject>Veterans</subject><subject>Workers</subject><subject>Workers compensation</subject><subject>Workplace</subject><issn>1351-0711</issn><issn>1470-7926</issn><issn>1470-7926</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><recordid>eNp9UU1v1DAUtBCIloUfwAVZ4sIlYPs5ccIFoYovqVIPwNmyHWfX28RebKer_fc43VJaJHqyn97M2DOD0EtK3lIKzbtgJ9tXjDCoKOmg6R6hU8oFqUTHmsflDjWtiKD0BD1LaUsIBQHsKTqBVrSsFs0pit-tmUcVcY7W9wk7j9dKq5312fngety7VIbk_BrrAzZhWiaVbY_3IV7amPDe5Q0ewx5rZS7xTjn_HiscbY6hUE12V7bwNiFmnPLcH56jJ4Mak31xc67Qz8-ffpx9rc4vvnw7-3heac6bXHV8EAMHplo9EMGNVqAY79qa0wZ6LaAHZhUv626AxghCW8aIqJVQbOhYCyv04ai7m3XJyRRLUY1yF92k4kEG5eT9jXcbuQ5XklLaCqhFUXhzoxDDr9mmLCeXjB1H5W2YkwTSEBB1W7Jfodf_QLdhjr74W1DQQSeuBR9A1aWUYm5B0SPKlARTtMPtnymRS_Hyuni5FC-PxRfOq7tmbxl_mi6A6gjQ0_bvq_8X_A1yE7my</recordid><startdate>20240501</startdate><enddate>20240501</enddate><creator>Mathieson, Stephanie</creator><creator>Collie, Alex</creator><creator>Maher, Christopher G</creator><creator>Abdel Shaheed, Christina</creator><creator>Xia, Ting</creator><creator>Gilbert, Stephen</creator><creator>Ferreira, Giovanni E</creator><creator>Di Donato, Michael F</creator><general>BMJ Publishing Group Ltd</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>L6V</scope><scope>M0S</scope><scope>M1P</scope><scope>M7S</scope><scope>NAPCQ</scope><scope>PATMY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PTHSS</scope><scope>PYCSY</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-6531-5949</orcidid><orcidid>https://orcid.org/0000-0002-7335-8842</orcidid><orcidid>https://orcid.org/0000-0002-1628-7857</orcidid><orcidid>https://orcid.org/0000-0001-5033-6248</orcidid><orcidid>https://orcid.org/0000-0003-2617-9339</orcidid><orcidid>https://orcid.org/0000-0003-1258-5125</orcidid><orcidid>https://orcid.org/0000-0002-8534-195X</orcidid></search><sort><creationdate>20240501</creationdate><title>Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study</title><author>Mathieson, Stephanie ; 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To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>38782576</pmid><doi>10.1136/oemed-2023-109369</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-6531-5949</orcidid><orcidid>https://orcid.org/0000-0002-7335-8842</orcidid><orcidid>https://orcid.org/0000-0002-1628-7857</orcidid><orcidid>https://orcid.org/0000-0001-5033-6248</orcidid><orcidid>https://orcid.org/0000-0003-2617-9339</orcidid><orcidid>https://orcid.org/0000-0003-1258-5125</orcidid><orcidid>https://orcid.org/0000-0002-8534-195X</orcidid><oa>free_for_read</oa></addata></record>
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source BMJ Journals - NESLi2
subjects Age groups
Analgesics
Antidepressants
Back injuries
Back Pain
Dispensing
Expenditures
Health services research
Injury analysis
Low back pain
Missing data
Narcotics
Pain
Pain management
Reimbursement
Socioeconomic factors
Socioeconomic status
Trends
Variables
Veterans
Workers
Workers compensation
Workplace
title Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study
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