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Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study
ObjectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid...
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Published in: | Occupational and environmental medicine (London, England) England), 2024-05, Vol.81 (5), p.245-251 |
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description | ObjectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period. |
doi_str_mv | 10.1136/oemed-2023-109369 |
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To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.</description><identifier>ISSN: 1351-0711</identifier><identifier>ISSN: 1470-7926</identifier><identifier>EISSN: 1470-7926</identifier><identifier>DOI: 10.1136/oemed-2023-109369</identifier><identifier>PMID: 38782576</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd</publisher><subject>Age groups ; Analgesics ; Antidepressants ; Back injuries ; Back Pain ; Dispensing ; Expenditures ; Health services research ; Injury analysis ; Low back pain ; Missing data ; Narcotics ; Pain ; Pain management ; Reimbursement ; Socioeconomic factors ; Socioeconomic status ; Trends ; Variables ; Veterans ; Workers ; Workers compensation ; Workplace</subject><ispartof>Occupational and environmental medicine (London, England), 2024-05, Vol.81 (5), p.245-251</ispartof><rights>Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ.</rights><rights>2024 Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Author(s) (or their employer(s)) 2024. Re-use permitted under CC BY. Published by BMJ. 2024</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-b446t-94f7f432a8bf074cba3a249854163db73d32ea4a8b9f36c701822075a7a2f9283</cites><orcidid>0000-0002-6531-5949 ; 0000-0002-7335-8842 ; 0000-0002-1628-7857 ; 0000-0001-5033-6248 ; 0000-0003-2617-9339 ; 0000-0003-1258-5125 ; 0000-0002-8534-195X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://oem.bmj.com/content/81/5/245.full.pdf$$EPDF$$P50$$Gbmj$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://oem.bmj.com/content/81/5/245.full$$EHTML$$P50$$Gbmj$$Hfree_for_read</linktohtml><link.rule.ids>230,314,776,780,881,3183,27901,27902,55321,77402,77428</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38782576$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mathieson, Stephanie</creatorcontrib><creatorcontrib>Collie, Alex</creatorcontrib><creatorcontrib>Maher, Christopher G</creatorcontrib><creatorcontrib>Abdel Shaheed, Christina</creatorcontrib><creatorcontrib>Xia, Ting</creatorcontrib><creatorcontrib>Gilbert, Stephen</creatorcontrib><creatorcontrib>Ferreira, Giovanni E</creatorcontrib><creatorcontrib>Di Donato, Michael F</creatorcontrib><title>Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study</title><title>Occupational and environmental medicine (London, England)</title><addtitle>Occup Environ Med</addtitle><addtitle>Occup Environ Med</addtitle><description>ObjectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.</description><subject>Age groups</subject><subject>Analgesics</subject><subject>Antidepressants</subject><subject>Back injuries</subject><subject>Back Pain</subject><subject>Dispensing</subject><subject>Expenditures</subject><subject>Health services research</subject><subject>Injury analysis</subject><subject>Low back pain</subject><subject>Missing data</subject><subject>Narcotics</subject><subject>Pain</subject><subject>Pain management</subject><subject>Reimbursement</subject><subject>Socioeconomic factors</subject><subject>Socioeconomic status</subject><subject>Trends</subject><subject>Variables</subject><subject>Veterans</subject><subject>Workers</subject><subject>Workers 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trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study</title><author>Mathieson, Stephanie ; Collie, Alex ; Maher, Christopher G ; Abdel Shaheed, Christina ; Xia, Ting ; Gilbert, Stephen ; Ferreira, Giovanni E ; Di Donato, Michael F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b446t-94f7f432a8bf074cba3a249854163db73d32ea4a8b9f36c701822075a7a2f9283</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Age groups</topic><topic>Analgesics</topic><topic>Antidepressants</topic><topic>Back injuries</topic><topic>Back Pain</topic><topic>Dispensing</topic><topic>Expenditures</topic><topic>Health services research</topic><topic>Injury analysis</topic><topic>Low back pain</topic><topic>Missing data</topic><topic>Narcotics</topic><topic>Pain</topic><topic>Pain management</topic><topic>Reimbursement</topic><topic>Socioeconomic factors</topic><topic>Socioeconomic status</topic><topic>Trends</topic><topic>Variables</topic><topic>Veterans</topic><topic>Workers</topic><topic>Workers compensation</topic><topic>Workplace</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mathieson, Stephanie</creatorcontrib><creatorcontrib>Collie, Alex</creatorcontrib><creatorcontrib>Maher, Christopher G</creatorcontrib><creatorcontrib>Abdel Shaheed, Christina</creatorcontrib><creatorcontrib>Xia, Ting</creatorcontrib><creatorcontrib>Gilbert, Stephen</creatorcontrib><creatorcontrib>Ferreira, Giovanni E</creatorcontrib><creatorcontrib>Di Donato, Michael F</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical 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Edition</collection><collection>Engineering Collection</collection><collection>Environmental Science Collection</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Occupational and environmental medicine (London, England)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mathieson, Stephanie</au><au>Collie, Alex</au><au>Maher, Christopher G</au><au>Abdel Shaheed, Christina</au><au>Xia, Ting</au><au>Gilbert, Stephen</au><au>Ferreira, Giovanni E</au><au>Di Donato, Michael F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study</atitle><jtitle>Occupational and environmental medicine (London, England)</jtitle><stitle>Occup Environ Med</stitle><addtitle>Occup Environ Med</addtitle><date>2024-05-01</date><risdate>2024</risdate><volume>81</volume><issue>5</issue><spage>245</spage><epage>251</epage><pages>245-251</pages><issn>1351-0711</issn><issn>1470-7926</issn><eissn>1470-7926</eissn><abstract>ObjectivesThe increase in gabapentinoid prescribing is paralleling the increase in serious harms. To describe the low back pain workers compensation population whose management included a gabapentinoid between 2010 and 2017, and determine secular trends in, and factors associated with gabapentinoid use.MethodsWe analysed claim-level and service-level data from the Victorian workers’ compensation programme between 1 January 2010 and 31 December 2017 for workers with an accepted claim for a low back pain injury and who had programme-funded gabapentinoid dispensing. Secular trends were calculated as a proportion of gabapentinoid dispensings per year. Poisson, negative binomial and Cox hazards models were used to examine changes over time in incidence and time to first dispensing.ResultsOf the 17 689 low back pain claimants, one in seven (14.7%) were dispensed at least one gabapentinoid during the first 2 years (n=2608). The proportion of workers who were dispensed a gabapentinoid significantly increased over time (7.9% in 2010 to 18.7% in 2017), despite a reduction in the number of claimants dispensed pain-related medicines. Gabapentinoid dispensing was significantly associated with an opioid analgesic or anti-depressant dispensing claim, but not claimant-level characteristics. The time to first gabapentinoid dispensing significantly decreased over time from 311.9 days (SD 200.7) in 2010 to 148.2 days (SD 183.1) in 2017.ConclusionsThe proportion of claimants dispensed a gabapentinoid more than doubled in the period 2010–2017; and the time to first dispensing halved during this period.</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd</pub><pmid>38782576</pmid><doi>10.1136/oemed-2023-109369</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-6531-5949</orcidid><orcidid>https://orcid.org/0000-0002-7335-8842</orcidid><orcidid>https://orcid.org/0000-0002-1628-7857</orcidid><orcidid>https://orcid.org/0000-0001-5033-6248</orcidid><orcidid>https://orcid.org/0000-0003-2617-9339</orcidid><orcidid>https://orcid.org/0000-0003-1258-5125</orcidid><orcidid>https://orcid.org/0000-0002-8534-195X</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Age groups Analgesics Antidepressants Back injuries Back Pain Dispensing Expenditures Health services research Injury analysis Low back pain Missing data Narcotics Pain Pain management Reimbursement Socioeconomic factors Socioeconomic status Trends Variables Veterans Workers Workers compensation Workplace |
title | Secular trends in gabapentinoid dispensing by compensated workers with low back pain: a retrospective cohort study |
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