A Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia in a 26-Year-Old Pregnant Woman

Acute lymphoblastic leukemia (ALL) is an uncommon and rapidly progressing blood cancer originating in the bone marrow, characterized by the abnormal proliferation of immature lymphocytes. Although most cases of ALL are observed in children, the disease pattern shows two peaks: one in early childhood...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-05, Vol.16 (5), p.e60679
Main Authors: Shaykh, Natalie, Patel, Falguni, Stachler, Luke, Ali, Kabeer, Tripathi, Vanshika, Rai, Oshin, Jacob, Rafik
Format: Article
Language:English
Subjects:
Adults
Biopsy
Blood tests
Bone marrow
Breast cancer
Cancer therapies
Case reports
Cesarean section
Chemotherapy
Chromosomes
Diagnostic tests
Fetuses
Hemoglobin
Inhibitor drugs
Kinases
Leukemia
Lymphocytes
Lymphoma
Medical Education
Medical prognosis
Neutrophils
Obstetrics/Gynecology
Oncology
Pediatrics
Pregnancy
Targeted cancer therapy
Transplants & implants
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Summary:Acute lymphoblastic leukemia (ALL) is an uncommon and rapidly progressing blood cancer originating in the bone marrow, characterized by the abnormal proliferation of immature lymphocytes. Although most cases of ALL are observed in children, the disease pattern shows two peaks: one in early childhood and another around the age of 50. Approximately a fifth to a third of adults diagnosed with ALL exhibit cytogenetic abnormalities involving the Philadelphia chromosome. Despite the existence of several studies on Philadelphia chromosome-positive ALL (Ph+ ALL), our case accentuates the use of a multi-disciplinary approach to treatment and involves a patient from a unique demographic.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.60679