Reverse Koebner Phenomenon in a Vitiligo Patient Treated With Radiotherapy

Radiation-induced hypopigmentation resulting in a skin condition similar to vitiligo is evident in limited studies. In contrast to the typical Koebner phenomenon where new lesions develop at the site of injury, the trauma-induced disappearance of a specific rash in a patient with an already-develope...

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Bibliographic Details
Published in:Curēus (Palo Alto, CA) CA), 2024-05, Vol.16 (5), p.e60771
Main Authors: Khan, Asma S, Badar, Quratulain, Siddiqui, Kaynat, Hanif, Shoaib, Lakhan, Hafeez
Format: Article
Language:English
Subjects:
Cancer
Case reports
Chronic illnesses
Cytokines
Dermatitis
Dermatology
Females
Literature reviews
Mucositis
Oncology
Oral cancer
Psoriasis
Radiation Oncology
Radiation therapy
Skin diseases
Squamous cell carcinoma
Trauma
Vitiligo
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Summary:Radiation-induced hypopigmentation resulting in a skin condition similar to vitiligo is evident in limited studies. In contrast to the typical Koebner phenomenon where new lesions develop at the site of injury, the trauma-induced disappearance of a specific rash in a patient with an already-developed skin disease is seen very rarely. This phenomenon is called "reverse Koebnerization" or "Koebner non-reaction." Herein, we submit a case of a 51-year-old female with already-developed vitiligo who came for treatment for carcinoma of the tongue with radiation therapy. Later, after the treatment, the patient developed a re-pigmentation of her skin.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.60771